从喜马拉雅红豆杉中分离出的两种新重排紫杉烷类化合物。

Two new rearranged taxoids from Taxus wallichiana ZUCC.

作者信息

Choudhary Muhammad Iqbal, Khan Abdul Majeed, Ashraf Muhammad

机构信息

International Center for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Pakistan.

出版信息

Chem Pharm Bull (Tokyo). 2002 Nov;50(11):1488-90. doi: 10.1248/cpb.50.1488.

DOI:10.1248/cpb.50.1488

PMID:12419915

Abstract

Two new rearranged taxane diterpenoids, 5alpha,7beta,10beta,13alpha-tetrahydroxy-2alpha,9alpha,15-triacetoxy-11(15-->1)-abeo-taxa-4(20), 11-diene (1) and 5alpha,9alpha,10beta,13alpha-tetraacetoxy-15-hydroxy-11(15-->1)-abeo-taxa-4(20), 11-diene (2) have been isolated from the barks of Taxus wallichiana. The structures of these compounds have been confirmed by modern spectroscopic techniques.

摘要

从喜马拉雅红豆杉树皮中分离出两个新的重排紫杉烷二萜类化合物，5α,7β,10β,13α-四羟基-2α,9α,15-三乙酰氧基-11(15→1)-去甲-紫杉-4(20),11-二烯（1）和5α,9α,10β,13α-四乙酰氧基-15-羟基-11(15→1)-去甲-紫杉-4(20),11-二烯（2）。这些化合物的结构已通过现代光谱技术得到证实。