Boyle Peter, Leon Maria Elena
Division of Epidemiology and Biostatistics, European Institute of Oncology, via Ripamonti 435, 20141 Milan, Italy.
Br Med Bull. 2002;64:1-25. doi: 10.1093/bmb/64.1.1.
Colorectal cancer is a important public health problem: there are nearly one million new cases of colorectal cancer diagnosed world-wide each year and half a million deaths. Recent reports show that, in the US, it was the most frequent form of cancer among persons aged 75 years and older. Given that the majority of cancers occur in elder people and with the ageing of the population in mind, this observation gives further impetus to investigating prevention and treatment strategies among this subgroup of the population. Screening research, recommendations and implementation is an obvious priority. While there are many questions to be resolved, it is apparent that many facets of colorectal cancer are becoming increasingly understood and prospects for prevention are becoming apparent. Achieving colorectal cancer control is the immediate challenge.
全球每年有近100万新诊断的结直肠癌病例,50万人死亡。最近的报告显示,在美国,它是75岁及以上人群中最常见的癌症形式。鉴于大多数癌症发生在老年人中,并且考虑到人口老龄化,这一观察结果进一步推动了对这一人群亚组的预防和治疗策略的研究。筛查研究、建议和实施显然是当务之急。虽然有许多问题有待解决,但很明显,结直肠癌的许多方面正越来越被人们所理解,预防的前景也越来越明显。实现结直肠癌控制是当前的挑战。