Hoppe V U, Kopplow H J, Wiskemann A
Arzneimittelforschung. 1975 May;25(5):817-25.
The protection against erythema belongs to the cosmetic effects which lend themselves to mathematical treatment. It is demonstrated -- on the basis of the optimal definitions given by Ellinger and Schulze -- that the calculation of the mean value of the light-protection factor Q as hitherto in use, does not correspond to the real frequency-distribution. On the contrary there exists, independent of the radiation source having sunlike characteristics and of the distance from the radiator, a binary-logarithmic standard distribution. With reference to the gradation principles of the human skin a transformation of the pertinent differences of area is necessary first, i.e. a transformation responding to the Gaussian standard distribution principle. Tables are presented concerning the transformation and the practical evaluation of the light-protection factor Q. By aid of these tables a standardization of the factors Q measured by different authors has been attained as well as a standardized statistical-mathematical analysis. The investigation of the threshold dose producing erythema on the unprotected human skin has revealed a superposition of three frequency-distribution types (showing logarithmic distribution, too) having different standard deviations. The results of this entirely statistical classification permit a safe forecast: the sunburn protection inherent in the human skin is compounded of several contributing factors which are interconnected multiplicatively, not additively.
对红斑的防护属于适合进行数学处理的美容效果。基于埃林格和舒尔茨给出的最佳定义可以证明,目前使用的光防护因子Q平均值的计算并不符合实际的频率分布。相反,存在一种与具有类太阳特征的辐射源以及与辐射器的距离无关的二元对数标准分布。参照人类皮肤的分级原则,首先需要对相关面积差异进行转换,即一种符合高斯标准分布原则的转换。文中给出了关于光防护因子Q转换及实际评估的表格。借助这些表格,实现了不同作者测量的因子Q的标准化以及标准化的统计数学分析。对未受保护的人体皮肤产生红斑的阈值剂量的研究揭示了三种具有不同标准差的频率分布类型(也呈对数分布)的叠加。这种完全基于统计的分类结果允许进行可靠预测:人体皮肤固有的晒伤防护是由几个相互作用的因素复合而成,这些因素是相乘而非相加的关系。