痘病毒直系同源簇（POCs）。

Poxvirus Orthologous Clusters (POCs).

作者信息

Ehlers Angelika, Osborne John, Slack Stephanie, Roper Rachel L, Upton Chris

机构信息

Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC V8W 3P6, Canada.

出版信息

Bioinformatics. 2002 Nov;18(11):1544-5. doi: 10.1093/bioinformatics/18.11.1544.

DOI:10.1093/bioinformatics/18.11.1544

PMID:12424130

Abstract

Poxvirus Orthologous Clusters (POCs) is a JAVA client-server application which accesses an updated database containing all complete poxvirus genomes; it automatically groups orthologous genes into families based on BLASTP scores for assessment by a human database curator. POCs has a user-friendly interface permitting complex SQL queries to retrieve interesting groups of DNA and protein sequences as well as gene families for subsequent interrogation by a variety of integrated tools: BLASTP, BLASTX, TBLASTN, Jalview (multiple alignment), Dotlet (Dotplot), Laj (local alignment), and NAP (nucleotide to amino acid alignment).

摘要

痘病毒直系同源簇（POCs）是一个Java客户端-服务器应用程序，它可以访问一个包含所有完整痘病毒基因组的更新数据库；它会根据BLASTP分数自动将直系同源基因分组为家族，以供人类数据库管理员评估。POCs具有用户友好的界面，允许进行复杂的SQL查询，以检索有趣的DNA和蛋白质序列组以及基因家族，随后可通过各种集成工具进行查询：BLASTP、BLASTX、TBLASTN、Jalview（多序列比对）、Dotlet（点阵图）、Laj（局部比对）和NAP（核苷酸到氨基酸比对）。