Weisburger John H
American Health Foundation, 1 Dana Road, Valhalla, NY 10595, USA.
Exp Biol Med (Maywood). 2002 Nov;227(10):924-7. doi: 10.1177/153537020222701014.
International research through epidemiological techniques has provided information on risk factors and preventive approaches in chronic disease. Causation complementing this base of knowledge with laboratory research on associated markers for each disease has outlined the possible mechanisms whereby risk factors and preventive conditions operate. Furthermore, laboratory research in animal models and cell cultures has expanded the appropriate elements associated with each condition. Individuals in the Mediterranean area present with a lower risk of several important chronic diseases, including coronary heart disease and a number of types of cancer associated with nutritional traditions, such as breast, colon, and prostate cancer. Vegetables and fruits in general and cooked tomatoes, together with olive oil, appear to be the nutritional traditions that account for this lower risk. These results lead to public health recommendations to consume more vegetables and, especially, cooked tomatoes with olive oil.
通过流行病学技术开展的国际研究提供了有关慢性病风险因素和预防方法的信息。利用针对每种疾病相关标志物的实验室研究对这一知识基础进行补充，因果关系阐明了风险因素和预防条件发挥作用的可能机制。此外，动物模型和细胞培养方面的实验室研究扩展了与每种情况相关的适当要素。地中海地区的人群患几种重要慢性病的风险较低，包括冠心病以及一些与营养传统相关的癌症类型，如乳腺癌、结肠癌和前列腺癌。一般而言，蔬菜和水果以及煮熟的番茄与橄榄油似乎是导致这种较低风险的营养传统。这些结果促使公共卫生领域建议人们多食用蔬菜，尤其是搭配橄榄油烹饪的番茄。
