Drozdzowska B, Pluskiewicz W, Tarnawska B
Department of Pathomorphology in Zabrze, Katowice, Poland.
Dentomaxillofac Radiol. 2002 Nov;31(6):361-7. doi: 10.1038/sj.dmfr.4600729.
The panoramic-based indices (Mandibular Cortical Index-MCI, the height of mandibular inferior cortex-IC (mm), Panoramic Mandibular Index-PMI, Mandibular Ratio-MR) were used to evaluate their diagnostic efficacy and to determine whether they correlate with bone mineral density (BMD (g/cm(2))) of the mandible and hip, and with ultrasound parameters of the calcaneus and hand phalanges in postmenopausal, edentulous women.
Basing on MCI women were divided into three subgroups differed in the appearance of the mandibular cortex (C1 n=6, C2 n=16, C3 n=8). BMD of the hip (neck-BMD, Ward's-BMD, trochanteric BMD) and mandible (m-BMD) were measured by dual-energy X-ray absorptiometry (DXA). Calcaneus using Achilles (Speed of Sound-SOS (m/s), Broadband Ultrasound Attenuation-BUA [dB/MHz], Stiffness Index-SI [%]) and hand phalanges (amplitude dependent speed of sound-Ad-SoS (m/s)) using DBM Sonic 1200 were assessed by Quantitative Ultrasound (QUS).
There were no significant differences between subgroups in parameters measured except for significant differences in m-BMD (P<0.01). Only m-BMD correlated significantly with DXA (r=0.43-0.45, P<0.05) and QUS (r=0.36-0.55, P<0.05) measurements excluding correlations with calcaneal SOS and trochanteric BMD. The ability of the mandibular variables to discriminate between normal and osteopenic/osteoporotic cases was assessed by calculating: specificity (ranging from 31 to 81%), sensitivity (ranging from 21 to 93%), negative and positive predictive values (ranging from 47 to 83% and 40 to 79%, respectively).
MCI is a simple three-graded classification of changes in the cortex but is not able to distinguish normal and osteopenic/osteoporotic postmenopausal edentulous women. The efficacy of the panoramic-based mandibular indices in diagnosing osteopenia/osteoporosis is low to moderate.
使用基于全景片的指标（下颌骨皮质指数-MCI、下颌骨下缘皮质高度-IC（mm）、全景下颌骨指数-PMI、下颌骨比率-MR）评估其诊断效能，并确定它们是否与绝经后无牙女性的下颌骨和髋部骨密度（BMD（g/cm²））以及跟骨和手部指骨的超声参数相关。
根据MCI将女性分为下颌骨皮质外观不同的三个亚组（C1 n = 6、C2 n = 16、C3 n = 8）。采用双能X线吸收法（DXA）测量髋部（颈部骨密度、沃德三角骨密度、大转子骨密度）和下颌骨（m-BMD）的骨密度。使用定量超声（QUS）通过跟腱评估跟骨（声速-SOS（m/s）、宽带超声衰减-BUA [dB/MHz]、硬度指数-SI [%]），并使用DBM Sonic 1200评估手部指骨（振幅依赖声速-Ad-SoS（m/s））。
除m-BMD存在显著差异（P<0.01）外，各亚组间测量参数无显著差异。仅m-BMD与DXA测量值（r = 0.43 - 0.45，P<0.05）和QUS测量值（r = 0.36 - 0.55，P<0.05）显著相关，不包括与跟骨SOS和大转子骨密度的相关性。通过计算评估下颌骨变量区分正常与骨质减少/骨质疏松病例的能力：特异性（范围为31%至81%）、敏感性（范围为21%至93%）、阴性和阳性预测值（分别范围为47%至83%和40%至79%）。
MCI是皮质变化的一种简单的三级分类，但无法区分正常与骨质减少/骨质疏松绝经后无牙女性。基于全景片的下颌骨指标在诊断骨质减少/骨质疏松方面的效能为低到中度。
