Esfandyari Tuba, Potter Jon W, Vaezi Michael F
Department of Gastroenterology, Center for Swallowing and Esophageal Disorders, Cleveland Clinic Foundation, Ohio 44195, USA.
Am J Gastroenterol. 2002 Nov;97(11):2733-7. doi: 10.1111/j.1572-0241.2002.07061.x.
The initial diagnostic approach for dysphagia is controversial. The choices include barium swallow (BaS) versus esophagogastroduodenoscopy (EGD). The aim of this study was to determine the clinical cost of establishing a diagnosis and treating dysphagia based on initial diagnostic approach (BaS vs EGD).
Clinical outcome of patients with undiagnosed dysphagia evaluated by either internists in a primary care clinic (n = 100) or gastroenterologists (n = 120) were determined based on the initial diagnostic test: BaS versus EGD. Final diagnoses in each group were determined based on any testing performed subsequent to the initial studies. Total cost in achieving the final diagnosis for each group were determined based on 2002 Medicare reimbursement cost.
BaS (66% and 62%) and EGD (34% and 38%) were ordered in equal prevalence by gastroenterologists and internists, respectively. Final diagnoses included: benign obstruction (37% and 36%), gastroesophageal reflux disease (GERD) (18% and 44%), achalasia (17% and 1%), nonspecific esophageal motility disorder (NSEMD) (17% and 11%), neoplasm (7% and 6%), and infectious esophagitis (4% and 2%) in subspecialty and primary care clinics, respectively. Motility disorders (NSEMD and achalasia) was diagnosed more often by gastroenterologists (40 of 120, 34%) than by internists (12 of 100, 12%) (p < 0.001). GERD was the predominant diagnosis made by internists (44 of 100, 44%) compared to gastroenterologists (22 of 120, 18%) (p < 0.001). Although the cost of diagnosing benign obstruction was less for BaS ($73 +/- 13) than EGD ($370 +/- 5, p < 0.001), subsequent therapy with dilation increased the cost for barium testing first (BaS $602 +/- 22 vs EGD $515 +/- 5, p < 0.02). Cost of diagnosis or treatment of esophageal dysmotility (achalasia/NSEMD) was significantly (p < 0.001) less using BaS as the initial test.
吞咽困难的初始诊断方法存在争议。选择包括吞咽钡剂造影(BaS)与食管胃十二指肠镜检查(EGD)。本研究的目的是确定基于初始诊断方法(BaS与EGD)来诊断和治疗吞咽困难的临床成本。
由基层医疗诊所的内科医生(n = 100)或胃肠病学家(n = 120)对未确诊吞咽困难的患者进行评估,根据初始诊断测试(BaS与EGD)确定临床结果。每组的最终诊断基于初始研究之后进行的任何检测。根据2002年医疗保险报销费用确定每组实现最终诊断的总成本。
胃肠病学家和内科医生分别以相同的比例开出BaS(66%和62%)和EGD(34%和38%)检查单。最终诊断包括:专科诊所和基层医疗诊所中分别为良性梗阻(37%和36%)、胃食管反流病(GERD)(18%和44%)、贲门失弛缓症(17%和1%)、非特异性食管动力障碍(NSEMD)(17%和11%)、肿瘤(7%和6%)以及感染性食管炎(4%和2%)。胃肠病学家诊断出的动力障碍(NSEMD和贲门失弛缓症)(120例中的40例,34%)比内科医生(100例中的12例,12%)更常见(p < 0.001)。与胃肠病学家(120例中的22例,18%)相比,内科医生诊断出的GERD更为常见(100例中的44例,44%)(p < 0.001)。尽管对于诊断良性梗阻,BaS的成本(73±13美元)低于EGD(370±5美元,p < 0.001),但随后的扩张治疗增加了钡剂检查的成本(BaS为602±22美元,而EGD为515±5美元,p < 0.02)。以BaS作为初始检查诊断或治疗食管动力障碍(贲门失弛缓症/NSEMD)的成本显著更低(p < 0.001)。
1)对于涉及异常动力的诊断和治疗,BaS的成本低于EGD。2)对于有良性梗阻病史的患者,具有治疗意图的初始EGD成本更低。3)基层医疗医生在其患者群体中比胃肠病学家更常将GERD和良性梗阻确定为吞咽困难的原因,这使得在这种情况下EGD是比目前使用的BaS更合理的初始检查。