Delgado del Rey M, Gómez Candela C, Cos Blanco A I, Iglesias Rosado C, Fernández Ibáñez M V, Castillo Rabaneda R, Mateo Lobo R, González Sánchez J A
Unidad de Nutrición Clínica, Hospital Universitario La Paz, Madríd.
Nutr Hosp. 2002 Sep-Oct;17(5):236-9.
Gastric cancer continues to be the second cause of cancer-related mortality in the world. Surgery is the only potentially curative therapy, although the adverse effects of surgery are considerable and include digestive symptoms, loss of appetite and malnutrition. Our study included 45 patients subjected to gastrectomy who were under treatment at our unit during 2000. The data given here refer to their first visit following surgery. The most frequent complications were diarrhoea (31%), pain (29%) and early dumping (24%). Other complications found were late dumping, nausea/vomiting and dysphagia. Anorexia appeared in 49% and 29% presented a negative attitude towards food. These complications give rise to insufficient food intake, leading to malnutrition, mainly marasmic in nature. Only 7% of the patients were normonourished, with 86% presenting slight or moderate malnutrition and 7% severe malnutrition. The mean Body Mass Index (BMI) of these patients was 20 +/- 3 kg/m2. The most frequent analytical alterations were anaemia with ferropenia and b12 deficit, and a reduction in the levels of zinc and retinol transporting protein. Many patients had impaired quality of life; 43% did not leave home and only 13% were able to work. Three groups were established depending on the time that had passed since the gastrectomy was performed before the first nutritional assessment (less than 3 months, from three months to a year, and over one year), without significant differences being found in any of the parameters studied. In this article we include recommendations for the nutritional handling and treatment of patients following gastrectomy.
胃癌仍然是全球癌症相关死亡的第二大原因。手术是唯一具有潜在治愈可能的治疗方法,尽管手术的不良反应相当大,包括消化症状、食欲不振和营养不良。我们的研究纳入了2000年期间在我们科室接受胃切除术治疗的45例患者。此处给出的数据是指他们术后首次就诊时的情况。最常见的并发症是腹泻(31%)、疼痛(29%)和早期倾倒综合征(24%)。发现的其他并发症有晚期倾倒综合征、恶心/呕吐和吞咽困难。49%的患者出现厌食,29%的患者对食物持消极态度。这些并发症导致食物摄入不足,进而引发营养不良,主要是消瘦型营养不良。只有7%的患者营养正常,86%的患者存在轻度或中度营养不良,7%的患者为重度营养不良。这些患者的平均体重指数(BMI)为20±3kg/m²。最常见的血液分析异常是缺铁性贫血和维生素B12缺乏,以及锌和视黄醇转运蛋白水平降低。许多患者的生活质量受损;43%的患者不出家门,只有13%的患者能够工作。根据首次营养评估前胃切除术后经过的时间(少于3个月、3个月至1年、超过1年)分为三组,在所研究的任何参数中均未发现显著差异。在本文中,我们给出了胃切除术后患者营养管理和治疗的建议。