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针对特发性帕金森病的亚历山大技术随机对照试验。

Randomized controlled trial of the Alexander technique for idiopathic Parkinson's disease.

作者信息

Stallibrass C, Sissons P, Chalmers C

机构信息

School of Integrated Medicine, University of Westminster, London, UK.

出版信息

Clin Rehabil. 2002 Nov;16(7):695-708. doi: 10.1191/0269215502cr544oa.

Abstract

OBJECTIVE

To determine whether the Alexander Technique, alongside normal treatment, is of benefit to people disabled by idiopathic Parkinson's disease.

DESIGN

A randomized controlled trial with three groups, one receiving lessons in the Alexander Technique, another receiving massage and one with no additional intervention. Measures were taken pre- and post-intervention, and at follow-up, six months later.

SETTING

The Polyclinic at the University of Westminster, Central London.

SUBJECTS

Ninety-three people with clinically confirmed idiopathic Parkinson's disease.

INTERVENTIONS

The Alexander Technique group received 24 lessons in the Alexander Technique and the massage group received 24 sessions of massage.

MAIN OUTCOME MEASURES

The main outcome measures were the Self-assessment Parkinson's Disease Disability Scale (SPDDS) at best and at worst times of day. Secondary measures included the Beck Depression Inventory and an Attitudes to Self Scale.

RESULTS

The Alexander Technique group improved compared with the no additional intervention group, pre-intervention to post-intervention, both on the SPDDS at best, p = 0.04 (confidence interval (CI) -6.4 to 0.0) and on the SPDDS at worst, p = 0.01 (CI -11.5 to -1.8). The comparative improvement was maintained at six-month follow-up: on the SPDDS at best, p = 0.04 (CI -7.7 to 0.0) and on the SPDDS at worst, p = 0.01 (CI -11.8 to -0.9). The Alexander Technique group was comparatively less depressed post-intervention, p = 0.03 (CI -3.8 to 0.0) on the Beck Depression Inventory, and at six-month follow-up had improved on the Attitudes to Self Scale, p = 0.04 (CI -13.9 to 0.0).

CONCLUSIONS

There is evidence that lessons in the Alexander Technique are likely to lead to sustained benefit for people with Parkinson's disease.

摘要

目的

确定亚历山大技术与常规治疗相结合是否对特发性帕金森病致残患者有益。

设计

一项三组随机对照试验,一组接受亚历山大技术课程,另一组接受按摩,还有一组不接受额外干预。在干预前后以及六个月后的随访时进行测量。

地点

伦敦市中心威斯敏斯特大学综合诊所。

受试者

93名临床确诊的特发性帕金森病患者。

干预措施

亚历山大技术组接受24节亚历山大技术课程,按摩组接受24次按摩治疗。

主要观察指标

主要观察指标为一天中最佳和最差状态下的帕金森病残疾自评量表(SPDDS)。次要指标包括贝克抑郁量表和自我态度量表。

结果

与无额外干预组相比,亚历山大技术组在干预前到干预后,最佳状态下的SPDDS有所改善,p = 0.04(置信区间(CI)-6.4至0.0),最差状态下的SPDDS也有所改善,p = 0.01(CI -11.5至-1.8)。在六个月的随访中,这种相对改善得以维持:最佳状态下的SPDDS,p = 0.04(CI -7.7至0.0),最差状态下的SPDDS,p = 0.01(CI -11.8至-0.9)。亚历山大技术组干预后相对抑郁程度较轻,贝克抑郁量表上p = 0.03(CI -3.8至0.0),在六个月的随访中,自我态度量表有所改善(p = 0.04,CI -13.9至0.0)。

结论

有证据表明,亚历山大技术课程可能会给帕金森病患者带来持续的益处。

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