Argandoña Victor H, Rovirosa Juana, San-Martín Aurelio, Riquelme Alejandro, Díaz-Marrero Ana R, Cueto Mercedes, Darias José, Santana Omar, Guadaño Ana, González-Coloma Azucena
Facultad de Ciencias, Universidad de Chile, Casilla 653 Santiago, Chile.
J Agric Food Chem. 2002 Nov 20;50(24):7029-33. doi: 10.1021/jf025857p.
In this work the antifeedant effects of the halogenated monoterpenes 1-13 were tested against several divergent insect species. These compounds have been isolated from Plocamium cartilagineum (6 was isolated as an acetyl derivative), except for 4, which was isolated from Pantoneura plocamioides. We have also included the semisynthetic derivatives 1a, 2a, and 7. Compounds 1, 1a, 2, 4, 5, 7, 8-10, and 13 were antifeedants against Leptinotarsa decemlineata with varying potencies. The aphids Myzus persicae and Ropalosiphum padi were strongly deterred in the presence of compounds 2, 12, and 13. This effect was correlated with the electronic recording of their probing behavior. Compounds 2 and 12 were toxic to L. decemlineata and had selective cytotoxicity to insect-derived Sf9 cells. None of the tested compounds showed phytotoxic effects. The antifeedant and cytotoxic effects of these compounds were compared with those of the polyhalogenated insecticide gamma-hexachlorocyclohexane (lindane).
在本研究中，测试了卤代单萜1-13对几种不同昆虫物种的拒食作用。这些化合物是从软骨藻（6是以乙酰衍生物形式分离得到）中分离出来的，除了4是从拟软骨藻潘通藻中分离得到。我们还纳入了半合成衍生物1a、2a和7。化合物1、1a、2、4、5、7、8-10和13对马铃薯甲虫具有不同效力的拒食作用。在化合物2、12和13存在的情况下，蚜虫桃蚜和禾谷缢管蚜受到强烈抑制。这种作用与它们取食行为的电子记录相关。化合物2和12对马铃薯甲虫有毒，并对昆虫来源的Sf9细胞具有选择性细胞毒性。所测试的化合物均未表现出植物毒性作用。将这些化合物的拒食和细胞毒性作用与多卤代杀虫剂γ-六氯环己烷（林丹）的作用进行了比较。
