Gerber M A
Hum Pathol. 1975 May;6(3):343-7. doi: 10.1016/s0046-8177(75)80096-7.
Four selected patients with progressive systemic sclerosis showed deposition of immunoglobulins and complement in diseased renal arteries and arterioles. Although three patients had hypertension, in two of these malignant, the third patient did not have hypertension over a four year period. These findings suggest that immune complexes may be involved in the pathogenesis of some cases of progressive systemic sclerosis, the primary target being the vascular system.
四名选定的进行性系统性硬化症患者在患病的肾动脉和小动脉中显示出免疫球蛋白和补体的沉积。虽然三名患者患有高血压，其中两名患者患有恶性高血压，但第三名患者在四年期间没有高血压。这些发现表明，免疫复合物可能参与了某些进行性系统性硬化症病例的发病机制，主要靶点是血管系统。
