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布替萘芬:其在浅表真菌病治疗中的应用进展

Butenafine: an update of its use in superficial mycoses.

作者信息

Gupta A K

机构信息

Division of Dermatology, Department of Medicine, Sunnybrook and Womens' College Health Sciences Center (Sunnybrook Site), University of Toronto, Toronto, Ontario, Canada.

出版信息

Skin Therapy Lett. 2002 Sep;7(7):1-2, 5.

Abstract

Butenafine is a synthetic benzylamine antifungal agent that may be fungicidal against susceptible organisms, e.g., dermatophytes. Butenafine may be effective and safe in the treatment of interdigital tinea pedis (apply twice daily for 1 week or once daily for 4 weeks), tinea corporis/tinea cruris (apply twice daily for 2 weeks), and pityriasis versicolor (apply once daily for 2 weeks). The effectiveness of the drug persists for at least 4 weeks following the discontinuation of therapy suggesting that there is some retention of the drug in the skin following termination of active therapy.

摘要

布替萘芬是一种合成苄胺类抗真菌药,对敏感菌如皮肤癣菌可能具有杀菌作用。布替萘芬治疗足趾间足癣(每日外用2次,连用1周或每日1次,连用4周)、体癣/股癣(每日外用2次,连用2周)和花斑糠疹(每日外用1次,连用2周)可能有效且安全。停药后,该药的疗效至少持续4周,这表明在停止积极治疗后,药物在皮肤中仍有一定的残留。

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