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布替萘芬:其在浅表真菌病治疗中的应用进展

Butenafine: an update of its use in superficial mycoses.

作者信息

Gupta A K

机构信息

Division of Dermatology, Department of Medicine, Sunnybrook and Womens' College Health Sciences Center (Sunnybrook Site), University of Toronto, Toronto, Ontario, Canada.

出版信息

Skin Therapy Lett. 2002 Sep;7(7):1-2, 5.

PMID:12432425
Abstract

Butenafine is a synthetic benzylamine antifungal agent that may be fungicidal against susceptible organisms, e.g., dermatophytes. Butenafine may be effective and safe in the treatment of interdigital tinea pedis (apply twice daily for 1 week or once daily for 4 weeks), tinea corporis/tinea cruris (apply twice daily for 2 weeks), and pityriasis versicolor (apply once daily for 2 weeks). The effectiveness of the drug persists for at least 4 weeks following the discontinuation of therapy suggesting that there is some retention of the drug in the skin following termination of active therapy.

摘要

布替萘芬是一种合成苄胺类抗真菌药,对敏感菌如皮肤癣菌可能具有杀菌作用。布替萘芬治疗足趾间足癣(每日外用2次,连用1周或每日1次,连用4周)、体癣/股癣(每日外用2次,连用2周)和花斑糠疹(每日外用1次,连用2周)可能有效且安全。停药后,该药的疗效至少持续4周,这表明在停止积极治疗后,药物在皮肤中仍有一定的残留。

相似文献

1
Butenafine: an update of its use in superficial mycoses.布替萘芬:其在浅表真菌病治疗中的应用进展
Skin Therapy Lett. 2002 Sep;7(7):1-2, 5.
2
Efficacy and safety of butenafine in superficial dermatophytoses (tinea pedis, tinea cruris, tinea corporis).布替萘芬治疗浅部皮肤癣菌病(足癣、股癣、体癣)的疗效与安全性。
J Indian Med Assoc. 2001 May;99(5):274-5.
3
Comparative efficacy of topical 1% butenafine and 1% clotrimazole in tinea cruris and tinea corporis: a randomized, double-blind trial.外用1%布替萘芬与1%克霉唑治疗股癣和体癣的疗效比较:一项随机双盲试验。
J Dermatolog Treat. 2005;16(5-6):331-5. doi: 10.1080/09546630500375783.
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Oxiconazole nitrate: pharmacology, efficacy, and safety of a new imidazole antifungal agent.硝酸奥昔康唑:一种新型咪唑类抗真菌药物的药理学、疗效及安全性
Clin Ther. 1991 Jan-Feb;13(1):126-41.
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Butenafine and superficial mycoses: current status.布替萘芬与浅表真菌病:现状
Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):999-1005. doi: 10.1517/17425255.4.7.999.
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Butenafine 1% cream in the treatment of tinea cruris: a multicenter, vehicle-controlled, double-blind trial.1%布替萘芬乳膏治疗股癣:一项多中心、赋形剂对照、双盲试验
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Once daily treatment with terbinafine 1% cream (Lamisil) for one week is effective in the treatment of tinea corporis and cruris. A placebo-controlled study.每日一次外用1%特比萘芬乳膏(兰美抒),持续一周,对体癣和股癣治疗有效。一项安慰剂对照研究。
Mycoses. 2001;44(7-8):300-6.
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Butenafine.布替萘芬
Drugs. 1998 Mar;55(3):405-12; discussion 413. doi: 10.2165/00003495-199855030-00006.
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Terbinafine. An update of its use in superficial mycoses.特比萘芬。其在浅表真菌病治疗中的应用进展
Drugs. 1999 Jul;58(1):179-202. doi: 10.2165/00003495-199958010-00018.
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Butenafine hydrochloride: for the treatment of interdigital tinea pedis.盐酸布替萘芬:用于治疗足趾间足癣。
Expert Opin Pharmacother. 2000 Mar;1(3):467-73. doi: 10.1517/14656566.1.3.467.

引用本文的文献

1
Allylamines, Benzylamines, and Fungal Cell Permeability: A Review of Mechanistic Effects and Usefulness against Fungal Pathogens.烯丙胺类、苄胺类与真菌细胞通透性:对真菌病原体作用机制及效用的综述
Membranes (Basel). 2022 Nov 22;12(12):1171. doi: 10.3390/membranes12121171.
2
Tinea versicolor: an updated review.花斑糠疹:最新综述
Drugs Context. 2022 Nov 14;11. doi: 10.7573/dic.2022-9-2. eCollection 2022.