Excoffier Laurent
Computational and Molecular Population Genetics (CMPG) Lab, Zoological Institute, University of Bern, Baltzerstrasse 6, 3012, Bern, Switzerland.
Curr Opin Genet Dev. 2002 Dec;12(6):675-82. doi: 10.1016/s0959-437x(02)00350-7.
Recent studies of large portions of the human genome support a recent origin of modern humans from an African stock after a bottleneck of moderate size followed by a range expansion out of Africa. Under this simple scenario, patterns of molecular diversity suggest that balancing selection could be more prevalent than positive selection in coding regions.
现代人类起源于非洲种群，经历了一次中等规模的瓶颈期，随后从非洲向外扩张。在这种简单的情况下，分子多样性模式表明，平衡选择在编码区可能比正选择更为普遍。
