一氧化氮与心力衰竭中的心肌功能：是友还是敌？
Nitric oxide and myocardial function in heart failure: friend or foe?
作者信息
Cotton J M, Kearney M T, Shah A M
机构信息
Department of Cardiology, Guy's King's & St Thomas's School of Medicine, King's College London (Denmark Hill Campus), London, UK.
出版信息
Heart. 2002 Dec;88(6):564-6. doi: 10.1136/heart.88.6.564.
Abstract
There is good evidence that nitric oxide has important autocrine/paracrine effects in the myocardium, serving to optimise and fine tune cardiac function
摘要
有充分证据表明，一氧化氮在心肌中具有重要的自分泌/旁分泌作用，有助于优化和微调心脏功能。
相似文献
1
Nitric oxide and myocardial function in heart failure: friend or foe?一氧化氮与心力衰竭中的心肌功能：是友还是敌？
Heart. 2002 Dec;88(6):564-6. doi: 10.1136/heart.88.6.564.
2
Role of myocardial neuronal nitric oxide synthase-derived nitric oxide in beta-adrenergic hyporesponsiveness after myocardial infarction-induced heart failure in rat.心肌神经元型一氧化氮合酶衍生的一氧化氮在大鼠心肌梗死后心力衰竭所致β-肾上腺素能反应低下中的作用
Circulation. 2004 Oct 19;110(16):2368-75. doi: 10.1161/01.CIR.0000145160.04084.AC. Epub 2004 Oct 4.
3
Nitric oxide in heart failure: friend or foe.心力衰竭中的一氧化氮：朋友还是敌人？
Heart Fail Rev. 2002 Oct;7(4):385-9. doi: 10.1023/a:1020767731450.
4
Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase.他汀类药物诱导内皮祖细胞动员、心肌新生血管形成、左心室功能改善以及实验性心肌梗死后存活的改善需要内皮型一氧化氮合酶。
Circulation. 2004 Oct 5;110(14):1933-9. doi: 10.1161/01.CIR.0000143232.67642.7A.
5
Antioxidant treatment for heart failure: friend or foe?心力衰竭的抗氧化治疗：是福是祸？
QJM. 2009 May;102(5):305-10. doi: 10.1093/qjmed/hcn160. Epub 2008 Dec 17.
6
[Nitric oxide and heart failure].[一氧化氮与心力衰竭]
Nihon Rinsho. 2004 Sep;62 Suppl 9:527-30.
7
Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice.塞利洛尔是一种血管舒张性β受体阻滞剂，可抑制压力超负荷诱导的心肌肥大，并通过一氧化氮依赖性机制预防小鼠发生心力衰竭。
Circulation. 2004 Aug 10;110(6):692-9. doi: 10.1161/01.CIR.0000137831.08683.E1. Epub 2004 Jul 19.
8
[Nitric oxide in the physiopathology of myocardial dysfunction in heart failure].[一氧化氮在心力衰竭心肌功能障碍的病理生理学中的作用]
Rev Port Cardiol. 2004 May;23 Suppl 2:II105-19.
9
Nitric oxide in acute renal failure: foe or friend?
Kidney Int Suppl. 1997 Oct;61:S39-40.
10
Soluble guanylyl cyclase activation improves progressive cardiac remodeling and failure after myocardial infarction. Cardioprotection over ACE inhibition.可溶性鸟苷酸环化酶激活可改善心肌梗死后进行性心脏重构和衰竭。优于血管紧张素转换酶抑制的心脏保护作用。
Basic Res Cardiol. 2014 Jul;109(4):421. doi: 10.1007/s00395-014-0421-1. Epub 2014 Jun 8.
引用本文的文献
1
The effect of astaxanthin supplementation on inflammatory markers, oxidative stress indices, lipid profile, uric acid level, blood pressure, endothelial function, quality of life, and disease symptoms in heart failure subjects.虾青素补充对心力衰竭患者炎症标志物、氧化应激指标、血脂谱、尿酸水平、血压、内皮功能、生活质量和疾病症状的影响。
Trials. 2024 Aug 1;25(1):518. doi: 10.1186/s13063-024-08339-8.
2
Dapagliflozin prevents ERK activation and SGLT2-dependent endoglin upregulation in a mechanically provoked cardiac injury model.达格列净可预防机械性心脏损伤模型中 ERK 的激活和 SGLT2 依赖性内格兰素的上调。
Physiol Rep. 2024 Apr;12(7):e15990. doi: 10.14814/phy2.15990.
3
NADPH Oxidases and Oxidative Stress in the Pathogenesis of Atrial Fibrillation.NADPH氧化酶与氧化应激在心房颤动发病机制中的作用
Antioxidants (Basel). 2023 Oct 6;12(10):1833. doi: 10.3390/antiox12101833.
4
Sodium-Glucose Cotransporter-2 Inhibitors Improve Heart Failure with Reduced Ejection Fraction Outcomes by Reducing Edema and Congestion.钠-葡萄糖协同转运蛋白2抑制剂通过减轻水肿和充血改善射血分数降低的心力衰竭结局。
Diagnostics (Basel). 2022 Apr 14;12(4):989. doi: 10.3390/diagnostics12040989.
5
Inflammation in Human Heart Failure: Major Mediators and Therapeutic Targets.人类心力衰竭中的炎症：主要介质与治疗靶点
Front Physiol. 2021 Oct 11;12:746494. doi: 10.3389/fphys.2021.746494. eCollection 2021.
6
Nitric oxide down-regulates voltage-gated Na channel in cardiomyocytes possibly through S-nitrosylation-mediated signaling.一氧化氮可能通过 S-亚硝基化介导的信号下调心肌细胞中的电压门控钠通道。
Sci Rep. 2021 May 28;11(1):11273. doi: 10.1038/s41598-021-90840-0.
7
A Low-Sodium Diet Boosts Ang (1-7) Production and NO-cGMP Bioavailability to Reduce Edema and Enhance Survival in Experimental Heart Failure.低钠饮食可促进血管紧张素 (1-7) 的产生和 NO-cGMP 的生物利用度，从而减轻水肿并提高实验性心力衰竭的存活率。
Int J Mol Sci. 2021 Apr 14;22(8):4035. doi: 10.3390/ijms22084035.
8
Short-Term Effects of Inhaled Nitric Oxide on Right Ventricular Flow Hemodynamics by 4-Dimensional-Flow Magnetic Resonance Imaging in Children With Pulmonary Arterial Hypertension.4D-Flow MRI 评价吸入一氧化氮对肺动脉高压患儿右心血流动力学的短期影响。
J Am Heart Assoc. 2021 Apr 20;10(8):e020548. doi: 10.1161/JAHA.120.020548. Epub 2021 Apr 6.
9
The Effect of Dietary Inorganic Nitrate Supplementation on Cardiac Function during Submaximal Exercise in Men with Heart Failure with Reduced Ejection Fraction (HFrEF): A Pilot Study.膳食无机硝酸盐补充对射血分数降低的心力衰竭（HFrEF）男性亚极量运动中心功能的影响：一项初步研究。
Nutrients. 2020 Jul 17;12(7):2132. doi: 10.3390/nu12072132.
10
Protective effect of nicotinamide and L-arginine against monocrotaline-induced pulmonary hypertension in rats: gender dependence.烟酰胺和L-精氨酸对大鼠野百合碱诱导的肺动脉高压的保护作用：性别依赖性
Pharmacol Rep. 2020 Oct;72(5):1334-1346. doi: 10.1007/s43440-020-00125-y. Epub 2020 Jul 6.
本文引用的文献
1
Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes.环磷酸鸟苷依赖性蛋白激酶在大鼠心肌细胞对外源性一氧化氮收缩反应中的作用。
J Physiol. 2002 Apr 15;540(Pt 2):457-67. doi: 10.1113/jphysiol.2001.014126.
2
No involvement of nitric oxide in the limitation of beta-adrenergic inotropic responsiveness during ischemia.缺血期间一氧化氮不参与β-肾上腺素能正性肌力反应的限制。
Am J Physiol Heart Circ Physiol. 2001 Dec;281(6):H2392-7. doi: 10.1152/ajpheart.2001.281.6.H2392.
3
Effects of nitric oxide synthase inhibition on Basal function and the force-frequency relationship in the normal and failing human heart in vivo.一氧化氮合酶抑制对正常及衰竭人心脏在体基础功能和力-频率关系的影响。
Circulation. 2001 Nov 6;104(19):2318-23. doi: 10.1161/hc4401.098515.
4
Endogenous nitric oxide mechanisms mediate the stretch dependence of Ca2+ release in cardiomyocytes.内源性一氧化氮机制介导心肌细胞中Ca2+释放的牵张依赖性。
Nat Cell Biol. 2001 Oct;3(10):867-73. doi: 10.1038/ncb1001-867.
5
Endogenous nitric oxide and myocardial adaptation to ischemia.
Circ Res. 2000 Jul 21;87(2):146-52. doi: 10.1161/01.res.87.2.146.
6
Contribution of caveolin protein abundance to augmented nitric oxide signaling in conscious dogs with pacing-induced heart failure.小窝蛋白丰度对起搏诱导的心力衰竭清醒犬一氧化氮信号增强的作用。
Circ Res. 2000 May 26;86(10):1085-92. doi: 10.1161/01.res.86.10.1085.
7
Paracrine and autocrine effects of nitric oxide on myocardial function.一氧化氮对心肌功能的旁分泌和自分泌作用。
Pharmacol Ther. 2000 Apr;86(1):49-86. doi: 10.1016/s0163-7258(99)00072-8.
8
Nitric oxide does not modulate the increases in blood flow, O2 consumption, or contractility during CaCl2 administration in canine hearts.在犬心脏给予氯化钙期间，一氧化氮不会调节血流量、氧气消耗或收缩力的增加。
Cardiovasc Res. 1999 Apr;42(1):232-9. doi: 10.1016/s0008-6363(98)00325-3.
9
Nitric oxide does not modulate whole body oxygen consumption in anesthetized dogs.
J Appl Physiol (1985). 1999 Jun;86(6):1944-9. doi: 10.1152/jappl.1999.86.6.1944.
10
Endomyocardial nitric oxide synthase and left ventricular preload reserve in dilated cardiomyopathy.扩张型心肌病中心肌内膜一氧化氮合酶与左心室前负荷储备
Circulation. 1999 Jun 15;99(23):3009-16. doi: 10.1161/01.cir.99.23.3009.
Zotero 插件