Ballarin B, Gazzano M, Hidalgo-Hidalgo De Cisneros J L, Tonelli D, Seeber R
Dipartimento di Chimica Fisica e Inorganica, Università di Bologna, INSTM, UdR Bologna, V. le Risorgimento, 4, Italy.
Anal Bioanal Chem. 2002 Nov;374(5):891-7. doi: 10.1007/s00216-002-1562-x. Epub 2002 Oct 18.
The behavior of cobalt phthalocyanine complexes incorporated inside an hydrotalcite-like clay (HT) or a sonogel-carbon composite has been investigated in order to develop chemically modified electrodes suitable for use as amperometric detectors. The electrocatalytic oxidation process of cysteine at this new electrode has been studied by cyclic voltammetry. For comparison, the oxidation of cysteine catalyzed by the cobalt phthalocyanine complex as a redox mediator, either dissolved in solution or entrapped inside the HT structure, has been followed by polarography. The sonogel-carbon composite electrode is stable and its response is repeatable. Cysteine oxidation is actually induced by the electrogenerated Co(III) complex, and the relevant anodic peak current varies linearly with cysteine concentration within the range 9.0x10(-4) to 1.0x10(-2) mol L(-1).
为了开发适用于安培检测器的化学修饰电极，研究了掺入类水滑石粘土（HT）或声凝胶-碳复合材料中的钴酞菁配合物的行为。通过循环伏安法研究了半胱氨酸在这种新电极上的电催化氧化过程。作为对比，通过极谱法跟踪了作为氧化还原介质的钴酞菁配合物催化的半胱氨酸氧化，该配合物可溶解在溶液中或包埋在HT结构内。声凝胶-碳复合电极稳定且响应可重复。半胱氨酸氧化实际上是由电生成的Co（III）配合物诱导的，相关阳极峰电流在9.0×10（-4）至1.0×10（-2）mol L（-1）范围内与半胱氨酸浓度呈线性变化。
