Jung W K
Arch Otorhinolaryngol. 1975 Nov 30;211(2):113-27. doi: 10.1007/BF01221119.
The perilymphatic space of the guinea pig's cochlea is filled within 1 to 3 min with an isotonic Ringer solution labelled with a radionuclide. The cochlea is neatly sealed immediately afterwards, thus causing only a minimal disturbance in the inner ear. The animal's cochlea is brought into the strict focus of a small detector as quickly as possible, the decay of activity is continuously controlled for 2 to 10 hrs. The radionuclides used are Cl36, Na22, and Tc99m. The decay of activity of the cochlea is strongly believed to accord to a simple exponential law; half lives range from about one to about three hours. Cl36 and Tc99m were used for the first time in studying cochlear kinetics.
豚鼠耳蜗的外淋巴间隙在1至3分钟内被标记有放射性核素的等渗林格溶液充满。之后立即将耳蜗妥善密封，从而对内耳仅造成极小的干扰。尽快将动物的耳蜗置于一个小型探测器的严格聚焦范围内，持续监测2至10小时的放射性活度衰减情况。所使用的放射性核素为氯36、钠22和锝99m。人们坚信耳蜗放射性活度的衰减符合简单的指数规律；半衰期约为1至3小时。氯36和锝99m首次用于研究耳蜗动力学。
