Frühwald H, Köllner W, Prohaska O
Laryngol Rhinol Otol (Stuttg). 1979 Sep;58(9):731-6.
After breathing a mix of 10% CO2 and 90% O2 or hyperbaric O2 (2 bar absolute) an appreciable rise of pO2 can be demonstrated by D.C. polarography in the scala tympani of the guinea pig chochlea. When test animals are made to breathe 100% pure O2 at normal pressure the rise of pO2 is significantly less pronounced. The observations made in these animal experiments suggest that the inhalation of CO2O2 currently constitutes the only valid inhalation treatment in acute inner ear deafness. Further compression of hyperbaric O2 is associated with a clear-cut rise of pO2. It should, however, be remembered that hyperbaric oxygen may produce toxic effects in various body tissues.
在豚鼠耳蜗鼓阶中，通过直流极谱法可证明，吸入10%二氧化碳和90%氧气的混合气体或高压氧（绝对压力2巴）后，动脉血氧分压（pO2）会有明显升高。当让实验动物在常压下呼吸100%纯氧时，pO2的升高明显不那么显著。这些动物实验中的观察结果表明，目前吸入二氧化碳 - 氧气混合气是急性内耳性聋唯一有效的吸入治疗方法。进一步增加高压氧的压力会使pO2明显升高。然而，应该记住，高压氧可能会在身体的各种组织中产生毒性作用。
