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颈椎前路手术后吞咽困难的发生率:一项前瞻性研究。

Incidence of dysphagia after anterior cervical spine surgery: a prospective study.

作者信息

Bazaz Rajesh, Lee Michael J, Yoo Jung U

机构信息

Spine Institute and Department of Orthopaedic Surgery, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA.

出版信息

Spine (Phila Pa 1976). 2002 Nov 15;27(22):2453-8. doi: 10.1097/00007632-200211150-00007.

Abstract

STUDY DESIGN

A prospective longitudinal study was conducted to evaluate dysphagia after anterior cervical spine surgery.

OBJECTIVES

To evaluate the incidence and natural history of dysphagia after anterior cervical spine surgery, and to identify risk factors for the development of postoperative dysphagia.

SUMMARY OF BACKGROUND DATA

The literature contains only retrospective evaluations of postoperative dysphagia. A wide range of incidence has been reported in these studies.

METHODS

Altogether, 249 consecutive patients undergoing anterior cervical spine surgery were eligible for the study. These patients were contacted 1, 2, 6, and 12 months after the procedure to evaluate swallowing. Risk factors such as age, gender, procedure type, hardware use, and number and location of surgical levels addressed were assessed.

RESULTS

Dysphagia incidences of 50.2%, 32.2%, 17.8%, and 12.5% were found at 1, 2, 6, and 12 months, respectively. At 6 months after the procedure, only 4.8% of the patients were experiencing moderate or severe dysphagia. Patient age, type of procedure (corpectomy vs. discectomy or primary vs. revision), hardware presence, and location of surgical levels were not statistically significant risk factors for the development of postoperative dysphagia. Female gender was significant for increased risk of dysphagia at 6 months. Surgery at multiple disc levels increased the risk of postoperative dysphagia at 1 and 2 months. The etiology of the dysphagia in most of the patients was unknown. However, vocal cord paresis was identified in 1.3% of the patients at 12 months.

CONCLUSIONS

Dysphagia after anterior cervical spine surgery is a common early finding. However, it decreases significantly by 6 months. The minority of patients experience moderate or severe symptoms by 6 months after the procedure. Female gender and multiple surgical levels could be identified as risk factors for the development of postoperative dysphagia.

摘要

研究设计

开展了一项前瞻性纵向研究,以评估颈椎前路手术后的吞咽困难情况。

目的

评估颈椎前路手术后吞咽困难的发生率及自然病程,并确定术后吞咽困难发生的危险因素。

背景资料总结

文献中仅有对术后吞咽困难的回顾性评估。这些研究报道的发生率范围很广。

方法

共有249例连续接受颈椎前路手术的患者符合本研究条件。在术后1个月、2个月、6个月和12个月对这些患者进行随访,以评估吞咽情况。评估了年龄、性别、手术类型、是否使用内固定器械以及手术节段数量和位置等危险因素。

结果

术后1个月、2个月、6个月和12个月的吞咽困难发生率分别为50.2%、32.2%、17.8%和12.5%。术后6个月时,仅有4.8%的患者存在中度或重度吞咽困难。患者年龄、手术类型(椎体次全切除术与椎间盘切除术或初次手术与翻修手术)、是否存在内固定器械以及手术节段位置并非术后吞咽困难发生的统计学显著危险因素。女性在术后6个月时发生吞咽困难的风险显著增加。多节段椎间盘手术会增加术后1个月和2个月时吞咽困难的风险。大多数患者吞咽困难的病因不明。然而,术后12个月时在1.3%的患者中发现了声带麻痹。

结论

颈椎前路手术后吞咽困难是常见的早期表现。不过,到6个月时会显著减轻。术后6个月时少数患者会出现中度或重度症状。女性和多节段手术可被确定为术后吞咽困难发生的危险因素。

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