Cherpitel Cheryl J
Public Health Institute, Alcohol Research Group, Berkeley, California 94709, USA.
Alcohol Clin Exp Res. 2002 Nov;26(11):1686-91. doi: 10.1097/01.ALC.0000036300.26619.78.
The purpose of this study was to compare the performance (sensitivity and specificity) of two brief screening instruments, CAGE and the Rapid Alcohol Problems Screen 4 (RAPS4), against ICD-10 and DSM-IV criteria for alcohol dependence and abuse in a representative sample of the U.S. adult household population by gender, ethnicity, and service utilization (emergency room and primary care) in the last year.
Data are from the Alcohol Research Group's 2000 National Alcohol Survey (n = 7612), which is a computer-assisted telephone interview survey of the U.S. general population 18 and over in all 50 U.S. states and the District of Columbia.
Sensitivity of the RAPS4 (0.86) was better than the CAGE (0.67) given similar specificity (0.95 vs. 0.98) and outperformed the CAGE for alcohol dependence across all gender, ethnic, and service utilization groups, except among blacks and Hispanics. The RAPS4 also performed equally well for females and males (0.88 vs. 0.85), whereas sensitivity of the CAGE was lower for females. Although sensitivity of the RAPS4 was better than the CAGE for alcohol abuse, sensitivity was low for both (0.56 and 0.36, respectively). When quantity-frequency (QF) questions (drinking five or more drinks on at least one occasion during the last year and drinking as often as once a month during the last year) were added to the RAPS4, the RAPS4-QF performed significantly better for alcohol abuse and outperformed the CAGE at a cut point of one across all gender, ethnic, and service utilization groups. The RAPS4-QF appeared to be most sensitive for alcohol abuse among both males and females reporting emergency room use (0.90).
The data suggest that the RAPS4 outperforms the CAGE in this general population sample. The addition of a QF question to the RAPS4 improves performance in relation to sensitivity for alcohol abuse, and the RAPS4 and RAPS4-QF may be the instruments of choice in brief screening for alcohol use disorders. Additional research is needed to further explore these issues.
本研究的目的是在按性别、种族以及过去一年中急诊室和初级保健服务利用情况分类的美国成年家庭人口代表性样本中,比较两种简短筛查工具(CAGE和快速酒精问题筛查4(RAPS4))相对于国际疾病分类第十版(ICD - 10)和精神疾病诊断与统计手册第四版(DSM - IV)中酒精依赖和滥用标准的表现(敏感性和特异性)。
数据来自酒精研究小组2000年的全国酒精调查(n = 7612),这是一项对美国所有50个州和哥伦比亚特区18岁及以上普通人群进行的计算机辅助电话访谈调查。
在特异性相似的情况下(0.95对0.98),RAPS4的敏感性(0.86)优于CAGE(0.67),并且在除黑人和西班牙裔之外的所有性别、种族和服务利用组中,RAPS4在酒精依赖方面的表现均优于CAGE。RAPS4在女性和男性中表现同样出色(0.88对0.85),而CAGE对女性的敏感性较低。尽管RAPS4在酒精滥用方面的敏感性优于CAGE,但两者的敏感性都较低(分别为0.56和0.36)。当将数量频率(QF)问题(过去一年中至少有一次饮用五杯或更多酒以及过去一年中每月饮酒一次或更多)添加到RAPS4中时,RAPS4 - QF在酒精滥用方面表现明显更好,并且在所有性别、种族和服务利用组中,在切点为一时优于CAGE。RAPS4 - QF在报告使用急诊室的男性和女性中对酒精滥用似乎最敏感(0.90)。
数据表明在该普通人群样本中RAPS4的表现优于CAGE。在RAPS4中添加QF问题可提高对酒精滥用敏感性方面的表现,并且RAPS4和RAPS4 - QF可能是酒精使用障碍简短筛查中的首选工具。需要进一步的研究来进一步探讨这些问题。