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免疫功能正常儿童中由新型隐球菌格特变种引起的中枢神经系统(CNS)感染的计算机断层扫描(CT)表现谱。

The spectrum of computerized tomography (CT) findings in central nervous system (CNS) infection due to Cryptococcus neoformans var. gattii in immunocompetent children.

作者信息

Correa Maria do Perpétuo Socorro Costa, Severo Luiz Carlos, Oliveira Flávio de Mattos, Irion Klaus, Londero Alberto Thomaz

机构信息

Núcleo de Medicina Tropical, Universidade Federal do Pará, PA, Brasil.

出版信息

Rev Inst Med Trop Sao Paulo. 2002 Sep-Oct;44(5):283-7. doi: 10.1590/s0036-46652002000500010.

DOI:10.1590/s0036-46652002000500010
PMID:12436170
Abstract

Cranial CT scans of eleven immunocompetent children with central nervous system (CNS) infection due to Cryptococcus neoformans var. gattii were retrospectively reviewed. These children had an average age of 8.8 years and positive culture for C. n. var. gattii in cerebrospinal fluid. The most common signs and symptoms were headache, fever, nuchal rigidity, nausea and vomiting. No normal cranial CT was detected in any patient. Hypodense nodules were observed in all patients. The remaining scan abnormalities were as follows: nine had diffuse atrophy, six had hydrocephalus, and five had hydrocephalus coexistent with diffuse atrophy.

摘要

对11名免疫功能正常、因新型隐球菌变种加蒂变种导致中枢神经系统(CNS)感染的儿童进行了回顾性头颅CT扫描。这些儿童的平均年龄为8.8岁,脑脊液中新型隐球菌变种加蒂的培养呈阳性。最常见的体征和症状为头痛、发热、颈项强直、恶心和呕吐。所有患者的头颅CT均未显示正常。所有患者均观察到低密度结节。其余扫描异常情况如下:9例有弥漫性萎缩,6例有脑积水,5例脑积水与弥漫性萎缩并存。

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