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免疫功能正常的非 HIV 患者的脑部 cryptococcosis 表现为占位性病变。

Cerebellar cryptococcosis characterized by a space-occupying lesion in an immunocompetent non-HIV patient.

机构信息

Department of Infectious Diseases, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People's Republic of China.

Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong ; Department of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People's Republic of China.

出版信息

Neuropsychiatr Dis Treat. 2014 Dec 19;11:21-4. doi: 10.2147/NDT.S75432. eCollection 2015.

DOI:10.2147/NDT.S75432
PMID:25552907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4277240/
Abstract

Central nervous system (CNS) cryptococcosis is an opportunistic fungal infection that typically occurs in patients with reduced immunological function, such as patients with AIDS, patients receiving organ transplants, or patients receiving corticosteroid and immunosuppressive therapy. CNS cryptococcosis rarely occurs in immunocompetent patients. CNS cryptococcosis is characterized by meningitis and encephalitis and occasionally forms isolated granulomas. Isolated cerebellar cryptococcoma is a rare condition, especially in immunocompetent patients, and the misdiagnosis rate is high. A definite diagnosis must be based on pathology. To raise awareness of this disease, the clinical data of a patient with cryptococcomas in the right side of the cerebellum are reported.

摘要

中枢神经系统(CNS)隐球菌病是一种机会性真菌感染,通常发生在免疫功能低下的患者中,如艾滋病患者、接受器官移植的患者或接受皮质类固醇和免疫抑制治疗的患者。CNS 隐球菌病很少发生在免疫功能正常的患者中。CNS 隐球菌病的特征是脑膜炎和脑炎,偶尔形成孤立性肉芽肿。孤立性小脑隐球菌瘤是一种罕见的情况,尤其是在免疫功能正常的患者中,误诊率很高。明确的诊断必须基于病理学。为了提高对这种疾病的认识,报告了一例右侧小脑隐球菌瘤患者的临床资料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3b/4277240/64d953183550/ndt-11-021Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3b/4277240/64d953183550/ndt-11-021Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a3b/4277240/64d953183550/ndt-11-021Fig1.jpg

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本文引用的文献

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The triple threat of cryptococcosis: it's the body site, the strain, and/or the host.隐球菌病的三重威胁:这是发病部位、菌株和/或宿主。
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