Kawamura Yoko, Mutsuga Motoh, Wakui Chiseko, Maitani Tamio
National Institute of Health Sciences: 1-18-1, Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
Shokuhin Eiseigaku Zasshi. 2002 Aug;43(4):215-20. doi: 10.3358/shokueishi.43.215.
The use of polyvinyl chloride gloves containing di(2-ethylhexyl) phthalate for food contact applications is restricted. In their place, polyvinyl chloride gloves containing non-phthalate plasticizers (PVC-NP) have been introduced. They contained unknown substances, so they were studied by GC/MS, HR-MS and NMR. The chemical structures of the unknown substances were confirmed to be diethylene glycol dibenzoate, triethylene glycol dibenzoate, dipropylene glycol dibenzoate, and alkylsulfonic acid phenyl ester, which are plasticizers. Including di-isononyl adipate, the contents of the plasticizers were 37.5-48.9% in the PVC-NP gloves, and their migration levels were 1,010-1,390 ppm into n-heptane. These are very high levels. These plasticizers are not widely used for food contact polyvinyl chloride throughout the world, and they have also not been registered as self-standards by Japanese manufacturers. Careful consideration will be necessary for the selection of a suitable plasticizer substitute.
含有邻苯二甲酸二（2-乙基己基）酯的聚氯乙烯手套用于食品接触用途受到限制。取而代之的是，已引入含有非邻苯二甲酸酯类增塑剂的聚氯乙烯手套（PVC-NP）。它们含有未知物质，因此通过气相色谱/质谱联用仪（GC/MS）、高分辨质谱（HR-MS）和核磁共振（NMR）进行了研究。未知物质的化学结构经证实为二乙二醇二苯甲酸酯、三乙二醇二苯甲酸酯、二丙二醇二苯甲酸酯和烷基磺酸苯酯，均为增塑剂。包括己二酸二异壬酯在内，PVC-NP手套中增塑剂的含量为37.5-48.9%，它们向正庚烷中的迁移水平为1010-1390 ppm。这些水平非常高。这些增塑剂在全球范围内并未广泛用于食品接触用聚氯乙烯，日本制造商也未将其注册为自有标准。在选择合适的增塑剂替代品时需要仔细考虑。
