Mitchell David A, Berovic Marin, Krieger Nadia
Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, Cx. P. 19041, Curitiba 81531-990, Parana, Brazil.
Biotechnol Annu Rev. 2002;8:183-225. doi: 10.1016/s1387-2656(02)08009-2.
Solid-state fermentation has centuries of history, but it is only in the last two decades that there has been a concerted effort to understand the bioprocessing issues involved and to apply them to a wide range of new products. This article provides an overview of the knowledge of solid-state bioprocessing that has been gained over this time. It shows that, although significant advances have been achieved in understanding of what controls process performance, much research is still required.
固态发酵已有数百年历史，但直到最近二十年，人们才齐心协力去了解其中涉及的生物加工问题，并将其应用于广泛的新产品中。本文概述了这段时间以来在固态生物加工方面所获得的知识。结果表明，尽管在理解控制工艺性能的因素方面已取得重大进展，但仍需开展大量研究。
