Boutsini S, Patakakis M, Burriel A R, Kontos B
The Institute of Infectious and Parasitic Animal Diseases, Laboratory of Parassitology, Athens, Greece.
New Microbiol. 2002 Oct;25(4):455-62.
Leishmaniasis, an important zoonosis, was serologically found to coexist with leptospirosis, another important zoonosis. The proportion of dogs positive to leishmaniasis was approximately 36%. Significant differences were observed between dogs located in greater Athens and those from rural Greece. Although dogs from either of the groups had a similar chance to be infected, rural dogs had significantly (p<0.01) higher titers (1/1,600) than dogs from greater Athens. Thirty two of the 344 dog serum samples examined had positive antibody titers against Leptospira spp., but only 13 of them had titers of 1/400 or over to both of the infectious agents. Whilst noted differences in the antibody titers of samples with evidence of leishmaniasis and leptospirosis were not observed their coexistence may complicate the clinical outcome of cases of mixed infection.
利什曼病是一种重要的人畜共患病，血清学研究发现它与另一种重要的人畜共患病钩端螺旋体病共存。利什曼病检测呈阳性的犬类比例约为36%。在大雅典地区的犬类和希腊农村地区的犬类之间观察到显著差异。尽管两组中的犬类感染几率相似，但农村犬类的滴度（1/1600）显著高于（p<0.01）大雅典地区的犬类。在检测的344份犬血清样本中，32份对钩端螺旋体属有阳性抗体滴度，但其中只有13份对两种感染因子的滴度均达到1/400或更高。虽然未观察到有利什曼病和钩端螺旋体病证据的样本在抗体滴度上存在明显差异，但它们的共存可能会使混合感染病例的临床结果复杂化。
