Taguchi A, Sharma N, Ali S Z, Dave B, Sessler D I, Kurz A
Department of Anaesthesia,Washington University, St. Louis, Missouri, USA.
Anaesthesia. 2002 Dec;57(12):1159-63. doi: 10.1046/j.1365-2044.2002.02832.x.
In most acupuncture studies it is difficult or even impossible to conduct a truly double-blind trial. However, this is possible when treatments are carried out on anaesthetised patients. Because acupuncture provides analgesia, we tested the hypothesis that needle stimulation of a combination of four ear acupoints would significantly reduce anaesthetic requirement. Ten healthy volunteers were anaesthetised with desflurane and randomly assigned to no treatment or acupuncture; the alternative treatment was given on a subsequent study day. Auricular acupuncture was performed with needles placed at the Shen Men, Thalamus, Tranquiliser and Master Cerebral Points on the right ear. Anaesthetic requirement, determined by the Dixon up-and-down method, was defined by the average desflurane concentration that prevented purposeful movement of the extremities in response to noxious electrical stimulation. Volunteers required a greater desflurane concentration to prevent movement on the control than on the acupuncture day: 4.9 (0.7; SD) vs. 4.4 (0.8) vol. %, p = 0.003. Acupuncture thus reduced anaesthetic requirement by 8.5 (7)%.
在大多数针灸研究中,进行真正的双盲试验是困难的甚至是不可能的。然而,当对麻醉患者进行治疗时,这是可行的。由于针灸具有镇痛作用,我们检验了以下假设:针刺四个耳部穴位的组合会显著降低麻醉药物的需求量。十名健康志愿者接受地氟醚麻醉,并随机分为不接受治疗组或针灸组;在随后的研究日给予替代治疗。耳部针灸是将针放置在右耳的神门、丘脑、镇静和脑点上进行的。通过Dixon上下法确定麻醉药物需求量,其定义为防止肢体对有害电刺激产生有目的运动的平均地氟醚浓度。与针灸日相比,志愿者在对照组中需要更高的地氟醚浓度来防止运动:4.9(0.7;标准差)对4.4(0.8)体积%,p = 0.003。因此,针灸使麻醉药物需求量降低了8.5(7)%。