Orrell R W, King R H M, Bowler J V, Ginsberg L
University Department of Clinical Neurosciences, Royal Free and University College Medical School, University College London, London, UK.
J Neurol Neurosurg Psychiatry. 2002 Dec;73(6):769-71. doi: 10.1136/jnnp.73.6.769.
The cause of peripheral neuropathy associated with tuberculosis is controversial. Possibilities include an immune mediated neuropathy, direct invasion of nerves, vasculitic neuropathy, compressive neuropathy, a meningitic reaction, and the toxic effects of antituberculous chemotherapy. This report describes the unusual finding of granulomas in the peripheral nerve of a patient with tuberculosis. The pathological findings were of a delayed hypersensitivity reaction, but with no more specific indications of the mechanism of the neuropathy.
与结核病相关的周围神经病变的病因存在争议。可能的原因包括免疫介导的神经病变、神经的直接侵犯、血管炎性神经病变、压迫性神经病变、脑膜炎反应以及抗结核化疗的毒性作用。本报告描述了一名结核病患者周围神经中出现肉芽肿这一不寻常的发现。病理结果显示为迟发型超敏反应，但对于神经病变的机制没有更具体的指征。
