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通过多维度方法确定的影响梅尼埃病患者生活质量的因素。

Factors influencing quality of life in patients with Ménière's disease, identified by a multidimensional approach.

作者信息

Söderman Anne-Charlotte Hessén, Bagger-Sjöbäck Dan, Bergenius Johan, Langius Ann

机构信息

Department of Otolaryngology, Karolinska Hospital, Stockholm, Sweden.

出版信息

Otol Neurotol. 2002 Nov;23(6):941-8. doi: 10.1097/00129492-200211000-00022.

DOI:10.1097/00129492-200211000-00022
PMID:12438860
Abstract

PURPOSE

To evaluate self-reported quality of life in Ménière's disease patients by a multidimensional approach and to identify predictors of the results.

STUDY DESIGN

Cross-sectional.

SETTING

Tertiary referral hospital centers.

PATIENTS

One hundred-twelve patients with Ménière's Disease.

MAIN OUTCOME MEASURE

Questionnaires concerning quality of life: Short Form 12 (SF-12) including the Mental Component Summary (MCS-12) and the Physical Component Summary (PCS-12), Hospital Anxiety and Depression Scale (HAD), Sickness Impact Profile (SIP), the Function Level Scale (FLS) from the American Association of Otology's criteria for reporting results of treatment of Ménière's Disease, Vertigo Symptom Scale (VSS), Hearing Disability Handicap scale (HDHS), Tinnitus Severity Questionnaire (TSQ), and Sense of Coherence (SOC) Scale.

RESULTS

The Ménière's patients rated their quality of life significantly worse than did healthy reference groups in both the physical and the psychosocial dimensions. The SOC affected the results of the HAD, the MCS-12, and the psychosocial dimension of the SIP. The VSS affected the results of PCS-12, both dimensions of the SIP, and the FLS. The speech perception subscale of the HDHS affected the MCS-12, and tinnitus severity affected the HAD anxiety subscale. The results of the FLS correlated with the physical dimension of quality of life.

CONCLUSION

The Ménière's patients experienced a worse quality of life than did healthy subjects. Vertigo mainly influenced the physical dimension, whereas tinnitus and hearing loss influenced the psychosocial dimension. Sense of coherence had an impact on the psychosocial dimension. The FLS was not sensitive enough to serve as an outcome of treatment results but needed to be complemented by quality of life instruments.

摘要

目的

采用多维度方法评估梅尼埃病患者自我报告的生活质量,并确定结果的预测因素。

研究设计

横断面研究。

研究地点

三级转诊医院中心。

患者

112例梅尼埃病患者。

主要观察指标

生活质量问卷:简短健康调查问卷12项版(SF-12),包括心理成分总结(MCS-12)和生理成分总结(PCS-12)、医院焦虑抑郁量表(HAD)、疾病影响量表(SIP)、美国耳科学会梅尼埃病治疗结果报告标准中的功能水平量表(FLS)、眩晕症状量表(VSS)、听力障碍残疾量表(HDHS)、耳鸣严重程度问卷(TSQ)以及连贯感(SOC)量表。

结果

梅尼埃病患者在生理和心理社会维度上对生活质量的评分均显著低于健康对照组。连贯感影响HAD、MCS-12以及SIP的心理社会维度的结果。VSS影响PCS-12、SIP的两个维度以及FLS的结果。HDHS的言语感知子量表影响MCS-12,耳鸣严重程度影响HAD焦虑子量表。FLS的结果与生活质量的生理维度相关。

结论

梅尼埃病患者的生活质量比健康受试者差。眩晕主要影响生理维度,而耳鸣和听力损失影响心理社会维度。连贯感对心理社会维度有影响。FLS作为治疗结果的指标不够敏感,需要用生活质量工具加以补充。

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