Blair Janet M, Fleming Patricia L, Karon John M
Epidemic Intelligence Service, Division of Applied Public Health Training, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
J Acquir Immune Defic Syndr. 2002 Nov 1;31(3):339-47. doi: 10.1097/00126334-200211010-00011.
We describe trends in AIDS incidence, survival, and deaths among racial/ethnic minority men who have sex with men (MSM).
We examined AIDS surveillance data for men diagnosed with AIDS from 1990 through 1999, survival trends from 1993 through 1997, and trends in AIDS incidence and deaths from 1996 to 1999, when highly active antiretroviral therapy (HAART) was introduced.
The percentage of racial/ethnic minority MSM with AIDS increased from 33% of 26,930 men in 1990 to 54% of 17,162 men in 1999. From 1996 through 1998, declines in AIDS incidence were smallest among black MSM (25%, from 66.2 to 49.5 per 100,000) and Hispanic MSM (29%, from 39.3 to 27.8), compared with white MSM (41%, from 17.9 to 10.5). Declines in deaths of MSM with AIDS were also smallest among black MSM (53%, from 39.7 to 18.6 deaths per 100,000) and Hispanic MSM (61%, 21.6 to 8.4), compared with white MSM (63%, 12.3 to 4.5). Survival improved each year for all racial/ethnic groups but was poorest for black MSM in all years.
Since the introduction of HAART, a combination of factors that include relatively higher infection rates in more recent years and differences in survival following AIDS diagnosis contribute to observed differences in trends in AIDS incidence and deaths among racial/ethnic minority MSM. Increased development of culturally sensitive HIV prevention services, and improved access to testing and care early in the course of disease are needed to further reduce HIV-related morbidity in racial/ethnic minority MSM.
我们描述了男男性行为者(MSM)中不同种族/族裔少数群体的艾滋病发病率、生存率及死亡情况的趋势。
我们研究了1990年至1999年被诊断为艾滋病的男性的艾滋病监测数据、1993年至1997年的生存趋势以及1996年至1999年引入高效抗逆转录病毒疗法(HAART)时的艾滋病发病率和死亡趋势。
患有艾滋病的种族/族裔少数群体男男性行为者的比例从1990年26,930名男性中的33%增至1999年17,162名男性中的54%。1996年至1998年期间,与白人男男性行为者(发病率从每10万人中17.9例降至10.5例,降幅为41%)相比,黑人男男性行为者(从每10万人中66.2例降至49.5例,降幅为25%)和西班牙裔男男性行为者(从每10万人中39.3例降至27.8例,降幅为29%)的艾滋病发病率降幅最小。与白人男男性行为者(死亡率从每10万人中12.3例降至4.5例,降幅为63%)相比,患有艾滋病的黑人男男性行为者(从每10万人中39.7例降至18.6例,降幅为53%)和西班牙裔男男性行为者(从每10万人中21.6例降至8.4例,降幅为61%)的艾滋病死亡降幅也最小。所有种族/族裔群体的生存率逐年提高,但黑人男男性行为者在各年份的生存率都是最差的。
自引入HAART以来,包括近年来相对较高的感染率以及艾滋病诊断后的生存差异等多种因素,导致了种族/族裔少数群体男男性行为者在艾滋病发病率和死亡趋势上出现了观察到的差异。需要进一步发展对文化敏感的艾滋病预防服务,并在疾病早期改善检测和护理的可及性,以进一步降低种族/族裔少数群体男男性行为者中与艾滋病相关的发病率。