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用于治疗氨基酸代谢紊乱相关疾病的蛋白质水解物制备进展(作者译)

[Progresses in the preparation of protein hydrolysates for the treatment of diseases related to aminoacid metabolism disorders (author's transl)].

作者信息

Crescenzi G S, Crocchioni G, D'Amicis G, Morisi A, Salvati G

出版信息

S TA NU. 1975 Mar-Apr;5(2):89-90.

PMID:1243947
Abstract

A method is described for the preparation of a protein hydrolysate to be used in diets for the treatment of the diseases primarily related to disorder of amino acid Metabolism. The method is based on the use of ion-exchange resins to avoid the use of mineral acids so that the time of hydrolysis is reduced to 7 hrs and aminoacids destroyed in the usual industrial preparations are protected. Yields of 70% are obtained with an hydrolysis ratio of 90%. These results allow the preparation of hydrolysates with a high chemical score in which the aminoacid responsible for the diseases primarily related to disorder of amino acid Metabolism symtoms have been removed.

摘要

描述了一种制备蛋白质水解物的方法,该水解物用于饮食中以治疗主要与氨基酸代谢紊乱相关的疾病。该方法基于使用离子交换树脂以避免使用无机酸,从而将水解时间缩短至7小时,并保护了在常规工业制备中被破坏的氨基酸。水解率为90%时,产率可达70%。这些结果使得能够制备具有高化学评分的水解物,其中导致主要与氨基酸代谢紊乱症状相关疾病的氨基酸已被去除。

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