Chasen Martin R, Ebrahim Iftikar O
Mary Potter Oncology Centre, Little Company of Mary Hospital, Groenkloof, Pretoria, Republic of South Africa.
Cancer Chemother Pharmacol. 2002 Nov;50(5):429-31. doi: 10.1007/s00280-002-0518-3. Epub 2002 Sep 27.
A 68-year-old female patient with advanced ovarian carcinoma collapsed whilst receiving a carboplatin and cyclophosphamide infusion. This reaction was considered to fit with coronary vasospasm. Hypersensitivity to carboplatin is a rare but real complication of therapy and should be considered in patients presenting with hyperacute changes on ECG whilst receiving carboplatin therapy.
一名68岁晚期卵巢癌女性患者在接受卡铂和环磷酰胺输注时突然晕倒。这种反应被认为符合冠状动脉痉挛。对卡铂过敏是一种罕见但确实存在的治疗并发症,对于在接受卡铂治疗时心电图出现超急性变化的患者应予以考虑。