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急性A型主动脉夹层半弓置换术的手术结果

Surgical results of hemiarch replacement for acute type A dissection.

作者信息

Ohtsubo Satoshi, Itoh Tsuyoshi, Takarabe Kyomi, Rikitake Kazuhisa, Furukawa Kojiro, Suda Hisao, Okazaki Yukio

机构信息

Department of Thoracic and Cardiovascular Surgery, Saga Medical School, Saga-City, Japan.

出版信息

Ann Thorac Surg. 2002 Nov;74(5):S1853-6; discussion S1857-63. doi: 10.1016/s0003-4975(02)04133-4.

Abstract

BACKGROUND

The appropriate surgical strategy for patients with an arch tear in acute type A dissection remains controversial. We retrospectively compared surgical results after hemiarch as compared with transverse aortic arch replacement in patients with an arch tear in acute type A dissection.

METHODS

The records of 88 patients who consecutively underwent graft replacement for acute type A dissection between 1989 and 2001 were reviewed. The patients were divided into three groups: patients with ascending aortic replacement (group AS, n = 41), those with hemiarch replacement (group HA, n = 23), and those with transverse arch replacement (group AR, n = 24). Operative mortality and morbidity and late outcome were compared among the three groups.

RESULTS

The overall early (30 day) mortality was 11.3% (10/88), and in-hospital mortality was 14.7% (13/88). In-hospital mortality in groups AS, HA, and AR were 7.3%, 8.6%, and 33.3%, respectively (p = 0.011). Cardiopulmonary bypass, circulatory arrest, and operation times were significantly shorter in group HA than in group AR (p < 0.001). A smaller amount of intraoperative transfusion of red blood cells (p = 0.0006) and fresh-frozen plasma (p = 0.0003) was needed in group HA than in group AR, and postoperative bleeding during the first 24 hours postoperatively was significantly less in group HA than in group AR (p = 0.0028). The incidence of postoperative coma did not differ among the three groups (p = 0.89), nor did the incidence of postoperative patent false channel in the descending thoracic aorta (p = 0.57). Actuarial survival rates after 5 years were significantly better in group HA (91.3% +/- 5.9%) than in group AR (44.4% +/- 14.3%, p = 0.018). Freedom from reoperation on the distal aorta within 5 years did not differ among the groups (p = 0.46).

CONCLUSIONS

Hemiarch replacement for acute type A dissection demonstrated favorable early and late outcome. The extent of graft replacement influenced surgical mortality and morbidity. Whenever the intimal tear is located in the lesser curvature of the transverse arch, hemiarch replacement is recommended to improve overall operative mortality and morbidity.

摘要

背景

急性A型主动脉夹层伴弓部撕裂患者的合适手术策略仍存在争议。我们回顾性比较了急性A型主动脉夹层伴弓部撕裂患者行半弓置换与全主动脉弓置换后的手术结果。

方法

回顾了1989年至2001年间连续接受急性A型主动脉夹层移植置换术的88例患者的记录。患者分为三组:升主动脉置换组(AS组,n = 41)、半弓置换组(HA组,n = 23)和全主动脉弓置换组(AR组,n = 24)。比较三组患者的手术死亡率、发病率及远期预后。

结果

总体早期(30天)死亡率为11.3%(10/88),住院死亡率为14.7%(13/88)。AS组、HA组和AR组的住院死亡率分别为7.3%、8.6%和33.3%(p = 0.011)。HA组的体外循环、循环阻断及手术时间均显著短于AR组(p < 0.001)。HA组术中输注红细胞量(p = 0.0006)和新鲜冰冻血浆量(p = 0.0003)均少于AR组,且HA组术后24小时内的术后出血量显著少于AR组(p = 0.0028)。三组患者术后昏迷发生率无差异(p = 0.89),降主动脉术后假性腔持续开放的发生率也无差异(p = 0.57)。HA组5年后的精算生存率(91.3% ± 5.9%)显著高于AR组(44.4% ± 14.3%,p = 0.018)。各组5年内远端主动脉再次手术的发生率无差异(p = 0.46)。

结论

急性A型主动脉夹层行半弓置换显示出良好的早期和远期预后。移植置换范围影响手术死亡率和发病率。当内膜撕裂位于主动脉弓小弯侧时,建议行半弓置换以改善总体手术死亡率和发病率。

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