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黄尿酸（XA）导致的异常色氨酸代谢与实验性糖尿病

Abnormal tryptophan metabolism and experimental diabetes by xanthurenic acid (XA).

作者信息

Kotake Y, Ueda T, Mori T, Igaki S, Hattori M

出版信息

Acta Vitaminol Enzymol. 1975;29(1-6):236-9.

PMID:1244098
Abstract
  1. Xanthurenic acid-insulin complex reduced insulin activity. 2) The antigenicity of xanthurenic acid-insulin was almost same as native insulin. 3) Saturated fat increased urinary xanthurenic acid in vitamin B6 deficiency.
摘要
  1. 黄尿酸-胰岛素复合物降低了胰岛素活性。2) 黄尿酸-胰岛素的抗原性与天然胰岛素几乎相同。3) 在维生素B6缺乏的情况下，饱和脂肪会增加尿中的黄尿酸。

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1
Abnormal tryptophan metabolism and experimental diabetes by xanthurenic acid (XA).黄尿酸（XA）导致的异常色氨酸代谢与实验性糖尿病
Acta Vitaminol Enzymol. 1975;29(1-6):236-9.
2
Xanthurenic acid and xanthurenic acid-8-methyl ether.黄尿酸和8-甲基醚黄尿酸
Med J Osaka Univ. 1968 Sep;19(1):13-23.
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Studies on the urinary excretion of xanthurenic acid in diabetics.糖尿病患者尿中黄尿酸排泄情况的研究。
Acta Vitaminol Enzymol. 1984;6(3):221-8.
4
Production of xanthurenic acid from tryptophan in pregnancy and in various states of nitrogen balance.孕期及不同氮平衡状态下色氨酸生成黄尿酸的情况。
Am J Physiol. 1957 Sep;190(3):419-24. doi: 10.1152/ajplegacy.1957.190.3.419.
5
A possible diabetogenic role for tryptophan metabolites and effects of xanthurenic acid on insulin.色氨酸代谢产物可能的致糖尿病作用及黄尿酸对胰岛素的影响。
Am J Clin Nutr. 1971 Jul;24(7):826-9. doi: 10.1093/ajcn/24.7.826.
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Xanthurenic acid, an abnormal metabolite of tryptophan and the diabetic symptoms caused in albino rats by its production.犬尿喹啉酸，一种色氨酸的异常代谢产物，以及其产生所导致的白化大鼠的糖尿病症状。
J Vitaminol (Kyoto). 1955 Feb 10;1(2):73-87. doi: 10.5925/jnsv1954.1.2_73.
7
Urinary excretion of xanthurenic acid and zinc in diabetes: (3). Occurrence of xanthurenic acid-Zn2+ complex in urine of diabetic patients and of experimentally-diabetic rats.糖尿病患者尿中黄尿酸和锌的排泄：(3). 糖尿病患者及实验性糖尿病大鼠尿液中黄尿酸-Zn2+复合物的存在情况。
Ital J Biochem. 1986 Jul-Aug;35(4):232-41.
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Kynurenine metabolism and xanthurenic acid formation in vitamin B6-deficient rat after tryptophan injection.色氨酸注射后维生素B6缺乏大鼠体内的犬尿氨酸代谢及黄尿酸生成
J Nutr Sci Vitaminol (Tokyo). 1989 Apr;35(2):111-22. doi: 10.3177/jnsv.35.111.
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Effects of two different loading doses of L-tryptophan on the urinary excretion of tryptophan metabolites in rats, mice and guinea pigs. Correlation with the enzyme activities.两种不同负荷剂量的L-色氨酸对大鼠、小鼠和豚鼠色氨酸代谢产物尿排泄的影响。与酶活性的相关性。
Ital J Biochem. 1987 May-Jun;36(3):194-203.
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Histological Changes in Pancreatic Islets of Animals with Experimental Diabetes Caused by Xanthurenic Acid under Condition of Suppression of Its Endogenous Synthesis.在抑制犬尿喹啉酸内源性合成的条件下，由犬尿喹啉酸引起的实验性糖尿病动物胰岛的组织学变化。
Bull Exp Biol Med. 2015 Sep;159(5):680-4. doi: 10.1007/s10517-015-3046-y. Epub 2015 Oct 14.

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