Roters Sigrid, Szurman Peter, Engels Bert F, Bartz-Schmidt Karl U, Krieglstein Gunter K
Center of Ophthalmology, University of Cologne, Germany.
Retina. 2002 Oct;22(5):581-8. doi: 10.1097/00006982-200210000-00008.
To determine the value of ultrasound biomicroscopy (UBM) in the assessment of ocular hypotony in cases where the underlying pathologic mechanism remains unclear after extensive clinical examination.
In a retrospective study, the records of 60 patients who had undergone UBM to elucidate the underlying structural abnormalities of chronic ocular hypotony (intraocular pressure of 0-8 mmHg) were evaluated. Most patients (47 of 60 eyes) had a history of intraocular surgery or of other ocular diseases (e.g., uveitis), and after careful clinical examination, the cause had remained unclear. All patients were observed up for a minimum of 12 months.
The associated pathoanatomy of the hypotony was demonstrated by UBM in 95% of the cases. Ciliary body abnormalities were present in 80% of the eyes. Therapeutic intervention was associated with restoration of normal ocular pressure in 50% of the cases. Often more than one intervention was necessary. A long duration of hypotony did not impede reaching the therapeutic goal of normalizing intraocular pressure and preventing phthisis.
Ultrasound biomicroscopy is a new tool for detecting the underlying structural abnormalities in ocular hypotony. In cases where clinical examination is not sufficient it can be of great help in deciding on a course of treatment.
对于经过全面临床检查后潜在病理机制仍不明确的低眼压病例,确定超声生物显微镜检查(UBM)在评估中的价值。
在一项回顾性研究中,对60例接受UBM检查以阐明慢性低眼压(眼压为0 - 8 mmHg)潜在结构异常的患者记录进行了评估。大多数患者(60只眼中的47只)有眼内手术史或其他眼部疾病史(如葡萄膜炎),经过仔细临床检查后,病因仍不明确。所有患者至少随访12个月。
95%的病例中,UBM显示了低眼压相关的病理解剖结构。80%的患眼存在睫状体异常。50%的病例中,治疗干预使眼压恢复正常。通常需要不止一种干预措施。低眼压持续时间长并不妨碍实现眼压正常化和预防眼球痨的治疗目标。
超声生物显微镜检查是检测低眼压潜在结构异常的一种新工具。在临床检查不足的情况下,它对确定治疗方案有很大帮助。