Watanabe N, Hirai N, Maehara T, Kawai K, Shimizu H, Miwakeichi F, Uchida S
Section of Psychiatry and Behavioral Science, Tokyo Medical Dental University, Bunkyo-ku Yushima 1-5-45, Tokyo 113-8549, Japan.
Neurosci Res. 2002 Dec;44(4):421-7. doi: 10.1016/s0168-0102(02)00159-1.
We have recorded electrocorticographic activities (ECoG) from subdural electrodes on the human medial temporal lobe (MTL) and basal temporal lobe (BTL) in epileptic patients during cognitive visual tasks designed to evoke the P300 event related potential (ERP). From those recordings we examined the event related gamma band oscillation (ERGBO) and P300 ERP. While P300 was predominantly observed in the MTL, ERGBO was observed in both MTL and BTL. Resembling to P300, ERGBO responses were more often observed following rare stimuli than frequent stimuli. In average responses the ERGBO to rare stimuli followed P300, beginning at 440.5 ms and continuing for about 100 ms. Past studies suggest P300 ERP component reflects a role in cognitive function. Since ERGBO in the present study appeared in different regions and at a different latency from P300, ERGBO may reflect a different physiological role in the cognitive process.
我们在癫痫患者进行旨在诱发P300事件相关电位（ERP）的认知视觉任务期间，记录了来自人类内侧颞叶（MTL）和基底颞叶（BTL）硬膜下电极的皮质电图活动（ECoG）。从这些记录中，我们研究了事件相关伽马波段振荡（ERGBO）和P300 ERP。虽然P300主要在MTL中观察到，但ERGBO在MTL和BTL中均有观察到。与P300相似，ERGBO反应在罕见刺激后比频繁刺激后更常被观察到。在平均反应中，对罕见刺激的ERGBO跟随P300，从440.5毫秒开始并持续约100毫秒。过去的研究表明P300 ERP成分反映了认知功能中的作用。由于本研究中的ERGBO出现在与P300不同的区域且潜伏期不同，ERGBO可能在认知过程中反映了不同的生理作用。
