Zhang Yuqing, Niu Jingbo, Kelly-Hayes Margaret, Chaisson Christine E, Aliabadi Piran, Felson David T
Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA 02118, USA.
Am J Epidemiol. 2002 Dec 1;156(11):1021-7. doi: 10.1093/aje/kwf141.
Osteoarthritis is one of the most common joint disorders in the elderly, yet few studies have targeted symptomatic osteoarthritis, especially symptomatic hand osteoarthritis. The authors conducted a survey in 1992-1993 among an elderly population to estimate the prevalence of symptomatic hand osteoarthritis and to assess its impact on grip strength and functional activities. Framingham Study subjects received hand radiographs and answered queries on joint symptoms. Functional activities were assessed using an interviewer-administered questionnaire. Grip strength and observed functional performance were evaluated using standard procedures. A hand joint was defined as having symptomatic osteoarthritis if both symptoms and radiographic evidence of osteoarthritis were present. Of 1,041 subjects aged 71-100 years (36% men), the prevalence of symptomatic hand osteoarthritis was higher in women (26.2%) than in men (13.4%). Compared with those without symptomatic hand osteoarthritis, subjects with the disease had 10% reduced maximal grip strength, reported more difficulty writing, handling, or fingering small objects (odds ratio = 3.4), and showed more self-reported and observed difficulty carrying a 10-pound (4.5-kg) bundle (odds ratio = 1.7 and 1.6, respectively). In conclusion, in the context of a remarkable paucity of data on the epidemiology of symptomatic hand osteoarthritis, this study suggests that symptomatic hand osteoarthritis is a common disease among elders and frequently impairs hand function.
骨关节炎是老年人中最常见的关节疾病之一,但针对有症状的骨关节炎,尤其是有症状的手部骨关节炎的研究却很少。作者在1992年至1993年期间对老年人群进行了一项调查,以估计有症状的手部骨关节炎的患病率,并评估其对握力和功能活动的影响。弗雷明汉研究的受试者接受了手部X光检查,并回答了有关关节症状的问题。使用由访员管理的问卷对功能活动进行评估。握力和观察到的功能表现采用标准程序进行评估。如果同时存在骨关节炎的症状和X光证据,则将手部关节定义为患有有症状的骨关节炎。在1041名年龄在71至100岁之间的受试者(36%为男性)中,有症状的手部骨关节炎的患病率女性(26.2%)高于男性(13.4%)。与没有有症状的手部骨关节炎的受试者相比,患有该疾病的受试者最大握力降低了10%,报告在书写、处理或操作小物体时更困难(优势比=3.4),并且在自我报告和观察到的携带10磅(4.5千克)重物方面显示出更多困难(优势比分别为1.7和1.6)。总之,在关于有症状的手部骨关节炎流行病学数据极为匮乏的情况下,本研究表明有症状的手部骨关节炎在老年人中是一种常见疾病,且经常损害手部功能。