Litwin M S, Relihan M, Sillin L
South Med J. 1975 Jun;68(6):694-8. doi: 10.1097/00007611-197506000-00008.
Stored human blood of varying age was passed through standard commercial blood transfusion filters (pore size, 170 mu) and Swank Dacron wool blood transfusion filters (pore size, 20mu). Passage through the Dacron filter resulted in a marked decrease in SFP and an increase in filter weight indicating removal of microaggregates which have been implicated as a cause of pulmonary insufficiency. The commercial filter tested did not appear to be effective in removing these harmful aggregates. On the basis of this research it is concluded that the Swank Dacron wool blood transfusion filter will prevent pulmonary microemboli during transfusion. Because aggregate removal appeared to be quantitative, it is recommended that no more than four units of blood be passed through each Dacron wool filter.
将不同保存时间的人体血液通过标准的商用输血过滤器(孔径170微米)和斯旺克涤纶羊毛输血过滤器(孔径20微米)。通过涤纶过滤器后,可滤过微粒蛋白(SFP)显著减少,过滤器重量增加,这表明已去除了被认为是导致肺功能不全原因的微聚体。所测试的商用过滤器似乎无法有效去除这些有害聚集体。基于这项研究得出的结论是,斯旺克涤纶羊毛输血过滤器可预防输血过程中的肺微栓塞。由于聚集体的去除似乎是定量的,因此建议每个涤纶羊毛过滤器过滤的血液单位数不超过四个。