Gulbranson Scott H, Wolfrey Jeffrey D, Raines John M, McNally Brian P
Good Samaritan Region Medical Center, Phoenix Children's Hospital, AZ 85006, USA.
Otolaryngol Head Neck Surg. 2002 Nov;127(5):463-4. doi: 10.1067/mhn.2002.129039.
Squamous cell carcinoma arising in a dentigerous cyst is a rare lesion with distinct histopathology and stringent criteria for diagnosis.(1,2) During the past century, <60 cases have been reported.(3) Of the previously documented cases, all have occurred in adults. We present the case of a squamous cell carcinoma arising in a dentigerous cyst in a 16-month-old girl. This case poses interesting questions regarding the pathophysiology of these tumors and highlights the importance of maintaining a high index of suspicion regardless of age when evaluating cystic lesions of the mandible and maxilla.
牙源性囊肿中发生的鳞状细胞癌是一种罕见病变，具有独特的组织病理学特征和严格的诊断标准。（1,2）在过去的一个世纪里，报告的病例少于60例。（3）在先前记录的病例中，均发生于成年人。我们报告一例16个月大女孩牙源性囊肿中发生鳞状细胞癌的病例。该病例就这些肿瘤的病理生理学提出了有趣的问题，并强调了在评估下颌骨和上颌骨囊性病变时，无论患者年龄如何，都要保持高度怀疑的重要性。
