Kampmann Christoph, Brzezinska Rita, Abidini Moji, Wenzel Anke, Wippermann Carl-Friedrich, Habermehl Pirmin, Knuf Markus, Schumacher Reinhard
Division of Paediatric Cardiology, University Children's Hospital of Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany.
Pediatr Radiol. 2002 Dec;32(12):839-43. doi: 10.1007/s00247-002-0825-1. Epub 2002 Oct 10.
It has been suggested that tungsten coils (TCs) may corrode 30 months after transcatheter embolisation (TCE). The aim of this study was to follow up children after TCE of aorto-pulmonary collaterals (APCs) with TCs.
Successful TCE of 99 APCs was performed in children using 152 TCs. Chest radiographs were obtained on the day after the procedure, after 3-6 months and 9-12 months, and yearly thereafter.
Mean follow-up was 39.3 months. After 9-12 months, radiographs revealed a decrease in radio-opacity and reduction of coil width in 29 (37.6%) of 77 APCs. After a mean of 25 months (range 13-51 months), there was loss of visibility in 44 (57.2%) of 77 TCs and a reduction in 29 (37.6%) of 77. After a mean of 39.3 months, all TCs showed decrease or loss of radio-opacity. Exponential function predicts complete biodegradation of 95% of TCs within 10 years after TCE (r2= 0.923). After a mean of 28.4 months, repeat catheterisation was performed in 24 APCs with TCs with decreased or lost radio-opacity. Recanalisation had occurred in 58.3%.
Dissolution occurred in 57.2% of TCs within a mean of 25 months, and within 39.3 months all TCs showed decrease or loss of radio-opacity. Recanalisation of closed APCs occurred in 58.3%.
有人提出，钨丝线圈（TCs）在经导管栓塞术（TCE）后30个月可能会发生腐蚀。本研究的目的是对接受TCs栓塞主-肺动脉侧支（APCs）的儿童进行随访。
使用152个TCs对99例儿童成功进行了APCs的TCE。术后第1天、3 - 6个月、9 - 12个月及此后每年进行胸部X线检查。
平均随访39.3个月。9 - 12个月后，X线片显示77个APCs中有29个（37.6%）的不透射线性降低和线圈宽度减小。平均25个月（范围13 - 51个月）后，77个TCs中有44个（57.2%）可见度丧失，29个（37.6%）减小。平均39.3个月后，所有TCs均显示不透射线性降低或丧失。指数函数预测TCE后10年内95%的TCs将完全生物降解（r2 = 0.923）。平均28.4个月后，对24个不透射线性降低或丧失的带TCs的APCs进行了再次导管插入术。再通发生率为58.3%。
平均25个月内57.2%的TCs发生溶解，39.3个月内所有TCs均显示不透射线性降低或丧失。闭合的APCs再通发生率为58.3%。
