Avakian A R, Brovkina I L, Lazarev A I, Uteshev B S
Biochemistry Department, Kursk State Medical University, ul. K. Marksa 3a, Kursk, 305041 Russia.
Eksp Klin Farmakol. 2002 Jul-Aug;65(4):42-6.
Introduced separately, preparations of the fat-soluble vitamins A, E and K decreased the expression of changes in the immunological reactivity and nonspecific resistance of Wistar rats after a 4-h swimming in water at a temperature of 10 +/- 2 degrees C. Joint administration of the vitamin preparations A + E or A + K normalized both the the immunological reactivity and nonspecific resistance of rats after cold swim test, while the joint introduction of vitamins E + K produces no such effect.
单独引入时,脂溶性维生素A、E和K的制剂可降低Wistar大鼠在10±2摄氏度的水中游泳4小时后免疫反应性和非特异性抵抗力的变化表达。维生素制剂A+E或A+K联合给药可使大鼠在冷泳试验后的免疫反应性和非特异性抵抗力恢复正常,而维生素E+K联合引入则无此效果。