Liu Y J, Li Z Q, Hao Y H
College of Veterinary Medicine, Nanjing Agricultural University, Peoples Republic of China.
J Vet Med B Infect Dis Vet Public Health. 2002 Oct;49(8):371-2. doi: 10.1046/j.1439-0450.2002.00569.x.
In vitro-hatched oncospheres of Taenia solium, prepared by the sodium hypochlorite method and adjusted to approximately 5 x 10(2)/2ml phosphate buffer saline, were injected intramuscularly or intravenously into normal Balb/c mice. When these mice were sacrificed 2 months later, all cysticerci were exclusively recovered in the lungs from the mice with intravenous inoculation, but not with intramuscular injection. A high infection rate of 76% was obtained and a total of 45 cysticerci were collected from 50 mice. Thirty-five cysticerci were mature and with normal appearance but the rest were either with abnormal appearance (4) or degenerated (6). These findings give strong evidence that T. solium oncospheres may migrate to the normal mouse lung through venous circulation and develop in this organ.
用次氯酸钠法制备的猪带绦虫体外孵育六钩蚴，调整至约5×10²/2ml磷酸盐缓冲盐水后，通过肌肉注射或静脉注射到正常Balb/c小鼠体内。2个月后处死这些小鼠时，在静脉接种的小鼠肺部仅发现了所有囊尾蚴，而肌肉注射的小鼠未发现。感染率高达76%，从50只小鼠中总共收集到45个囊尾蚴。35个囊尾蚴成熟且外观正常，但其余的要么外观异常（4个），要么已退化（6个）。这些发现有力地证明，猪带绦虫六钩蚴可能通过静脉循环迁移到正常小鼠肺部并在该器官中发育。
