Inhibition by ajoene of skin-tumor promotion in mice.
作者信息
Nishikawa Tomoaki, Yamada Norihiko, Hattori Atsuhiko, Fukuda Hiroyuki, Fujino Tsuchiyoshi
机构信息
Biodevelopment Division, Central Institute, Nagoya Seiraku Co., Ltd., 310 Nakasuna-cho, Tempaku-ku, Nagoya, Aichi 468-0065, Japan.
出版信息
Biosci Biotechnol Biochem. 2002 Oct;66(10):2221-3. doi: 10.1271/bbb.66.2221.
PMID:12450136
Abstract
Ajoene, a major compound containing sulfur in oil-macerated garlic products, inhibited in a two-stage carcinogenesis test on mouse skin. Treatment with ajoene suppressed skin tumor formation, depending on the amount. In particular, the group treated with 250 microg of ajoene had only 4.9% the number of tumors per mouse compared with the control group at 18 weeks.
摘要
Zotero 插件