Lowery Kath, Ballard Clive, Rodgers Helen, McLaren Andrew, O'Brien John, Rowan Elise, Stephens Sally
Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK.
Age Ageing. 2002 Nov;31 Suppl 3:24-7. doi: 10.1093/ageing/31.suppl_3.24.
Although cognitive decline is frequent after stroke, there has been very little work focussing upon older age groups, in whom the majority of strokes occur.
To determine whether cognitive decline is more common in older (>75) compared to younger (<75) stroke survivors.
A cohort of 360 stroke survivors of all ages from a stroke register in Newcastle, UK, were assessed prospectively at 3 time points over 1 year with a standardized battery. Dementia was diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria.
The overall one year prevalence of dementia was 23%, but rose from 7% in the under 65's to 53% in over 85's. People over 75 were significantly more likely to have dementia (Odds Ratio 8.9, 95% Confidence Intervals 4.1-19.1).
The striking age related increase in the prevalence of dementia has important implications for service planning and clinical management.
尽管中风后认知功能下降很常见，但针对老年人群体（大多数中风发生在该群体中）的研究却很少。
确定与年轻（<75岁）中风幸存者相比，认知功能下降在老年（>75岁）中风幸存者中是否更常见。
对来自英国纽卡斯尔中风登记处的360名各年龄段的中风幸存者进行队列研究，在1年的时间里分3个时间点使用标准化测试组合进行前瞻性评估。根据《精神障碍诊断与统计手册》第四版标准诊断痴呆症。
痴呆症的总体一年患病率为23%，但从65岁以下人群中的7%上升至85岁以上人群中的53%。75岁以上的人患痴呆症的可能性显著更高（优势比8.9，95%置信区间4.1 - 19.1）。
痴呆症患病率随年龄显著增加，这对服务规划和临床管理具有重要意义。
