Penzel T, Fricke R, Jerrentrup A, Peter J H, Vogelmeier C
Klinik für Innere Medizin-Pneumologie, Klinikum, Philipps-Universität, Marburg, Deutschland.
Biomed Tech (Berl). 2002;47 Suppl 1 Pt 1:315-7. doi: 10.1515/bmte.2002.47.s1a.315.
Sleep related breathing disorders have been recognized as a risk factor for cardiovascular disorders. Peripheral arterial tonometry (PAT) allows to monitor vasoconstriction on the finger continuously and non-invasively. We investigated whether the rapid changes of autonomous function can be assessed by PAT. In 21 patients with obstructive sleep apnea and arterial hypertension we recorded PAT in parallel to cardiorespiratory polysomnography and invasive arterial blood pressure. The correlation between periodic PAT attenuations and the total number of apneas (r = 0.656, p < 0.01) and the total number of cortical arousal (r = 0.583, p < 0.01) were significant. The PAT signal cannot substitute blood pressure but allows a good recognition of apneas and subcortical arousal and gives additional information on changes of sympathetic and parasympathetic tone during sleep.
睡眠相关呼吸障碍已被确认为心血管疾病的一个危险因素。外周动脉张力测量法(PAT)能够连续且无创地监测手指上的血管收缩情况。我们研究了自主功能的快速变化是否可以通过PAT进行评估。在21例阻塞性睡眠呼吸暂停合并动脉高血压患者中,我们在进行心肺多导睡眠图和有创动脉血压测量的同时记录了PAT。周期性PAT衰减与呼吸暂停总数(r = 0.656,p < 0.01)以及皮层觉醒总数(r = 0.583,p < 0.01)之间的相关性显著。PAT信号不能替代血压,但能很好地识别呼吸暂停和皮层下觉醒,并提供有关睡眠期间交感神经和副交感神经张力变化的额外信息。