Tomar R H
Int Arch Allergy Appl Immunol. 1976;50(2):220-4. doi: 10.1159/000231499.
Delayed skin reactor (DSR), the material in streptokinase-streptodornase responsible for eliciting delayed hypersensitivity reactions in man, is stable as a lyophilized powder or when stored at -70 degrees C. Storage at a pH above or below 6.0 leads to a decrease in the ability of DSR to stimulate lymphocyte proliferation in vitro. Its molecular weight is 30,000 as estimated by sodium dodecyl sulfate gel electrophoresis and it is composed of approximately 260 amino acid residues without apparent sulfhydryl-bridged subunits. The extinction coefficient of DSR (A 1% 280 nm) is 2.6.
迟发性皮肤反应原（DSR）是链激酶-链道酶中引起人类迟发性超敏反应的物质，作为冻干粉末或在-70℃储存时是稳定的。在pH高于或低于6.0的条件下储存会导致DSR在体外刺激淋巴细胞增殖的能力下降。通过十二烷基硫酸钠凝胶电泳估计其分子量为30,000，它由大约260个氨基酸残基组成，没有明显的巯基桥接亚基。DSR的消光系数（A 1% 280nm）为2.6。
