大鼠脊髓中甘氨酸特异性突触。通过电子显微镜放射自显影鉴定。
Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography.
作者信息
Price D L, Stocks A, Griffin J W, Young A, Peck K
出版信息
J Cell Biol. 1976 Feb;68(2):389-95. doi: 10.1083/jcb.68.2.389.
Abstract
Glycine, an inhibitory transmitter in spinal cord, is taken up into specific nerve terminals by means of a unique high-affinity uptake system. In this study, [3H]glycine was directly microinjected into rat ventral horn in vivo and electron microscope autoradiography used to localize the label in various anatomic compartments. Quantiative analysis showed that [3H]glycine labeled a high proportion of axosomatic and axodendritic synapses which presumably act to inhibit spinal motor neurons.
摘要
甘氨酸是脊髓中的一种抑制性递质，它通过一种独特的高亲和力摄取系统被摄取到特定的神经末梢中。在本研究中，将[3H]甘氨酸直接活体微量注射到大鼠腹角，并使用电子显微镜放射自显影术将标记定位在各种解剖区域。定量分析表明，[3H]甘氨酸标记了很大比例的轴体突触和轴树突触，这些突触可能起到抑制脊髓运动神经元的作用。
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本文引用的文献
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