稻瘟病菌中胱硫醚β-合酶基因CBS1的分子特征分析
Molecular characterization of a cystathionine beta-synthase gene, CBS1, in Magnaporthe grisea.
作者信息
Lo Sze Chung Clive, Hamer Lisbeth, Hamer John E
机构信息
Microbial Research, Paradigm Genetics, Inc., Research Triangle Park, North Carolina 27709, USA.
出版信息
Eukaryot Cell. 2002 Apr;1(2):311-4. doi: 10.1128/EC.1.2.311-314.2002.
Abstract
CBS1 from Magnaporthe grisea is a structural and functional homolog of the cystathionine beta-synthase (CBS) gene from Saccharomyces cerevisiae. Our studies indicated that M. grisea can utilize homocysteine and methionine through a CBS-independent pathway. The results also revealed responses of M. grisea to homocysteine that are reminiscent of human homocystinuria.
摘要
稻瘟病菌的CBS1是酿酒酵母中胱硫醚β-合酶（CBS）基因的结构和功能同源物。我们的研究表明，稻瘟病菌可以通过一条不依赖CBS的途径利用同型半胱氨酸和甲硫氨酸。结果还揭示了稻瘟病菌对同型半胱氨酸的反应，这让人联想到人类的同型胱氨酸尿症。
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