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1型糖尿病患者的乳糜泻筛查

Screening for coeliac disease in type 1 diabetes.

作者信息

Holmes G K T

机构信息

Department of Medicine, Derbyshire Royal Infirmary, Derby, UK.

出版信息

Arch Dis Child. 2002 Dec;87(6):495-8. doi: 10.1136/adc.87.6.495.

Abstract

The average prevalence of coeliac disease among children with diabetes mellitus in 26 reports was 4.5% (0.97-16.4%). Malabsorption, unstable diabetes, and growth failure, indicate that coeliac disease may be present. Even those who are apparently asymptomatic may have subtle complaints indicative of coeliac disease if a careful history is taken. Ill health may only be recognised in retrospect following the benefits conferred by a gluten free diet. For these reasons it is recommended that a screening programme should be instituted to detect coeliac disease in these children. Parents and where possible children themselves, should be fully involved at all stages of the screening, diagnostic, and treatment process.

摘要

26份报告中糖尿病患儿乳糜泻的平均患病率为4.5%(0.97 - 16.4%)。吸收不良、糖尿病不稳定和生长发育迟缓提示可能存在乳糜泻。即使是那些明显无症状的患儿,如果仔细询问病史,也可能有提示乳糜泻的细微症状。只有在采用无麸质饮食后病情好转,才可能回顾性地认识到健康问题。基于这些原因,建议开展筛查项目以检测这些患儿是否患有乳糜泻。家长以及可能的话患儿自身,应全面参与筛查、诊断和治疗过程的各个阶段。

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