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营销在药物研发中的作用。

The role of marketing in pharmaceutical research and development.

作者信息

Calfee John E

机构信息

American Enterprise Institute, Washington, USA.

出版信息

Pharmacoeconomics. 2002;20 Suppl 3:77-85. doi: 10.2165/00019053-200220003-00008.

DOI:10.2165/00019053-200220003-00008
PMID:12457428
Abstract

Pharmaceutical marketing, which is primarily targeted at physicians, has been criticised because it may distort physician prescribing and thus potentially raise costs and/or worsen health. An alternative view, presented in this paper, is that successful marketing of pharmaceuticals can improve consumer welfare by increasing incentives for research and development (R&D) investment and by providing guidance to R&D to make it more consistent with consumer preferences. There are a number of arguments that support this view, despite impediments to pharmaceutical marketing such as the prohibited dissemination of off-label information in the US, difficulties in estimating potential pharmaceutical demand, and the long time lag between demand assessment and the introduction of new drugs. For example, physicians are often slow to modify their prescribing practices, even when new evidence-based practice guidelines are issued by prestigious organisations. Pharmaceutical promotion is likely to be particularly valuable because information plays a key role, is highly technical, and can change rapidly. Even consumer advertising can potentially improve health, for example, by improving patient compliance with drug therapy. In addition to disseminating information about the benefits of new therapies, an essential (and perhaps unique) role for pharmaceutical promotion is to encourage physicians and payers to pay closer attention to consumer needs (i.e. willingness to pay) for new medical technology. Moreover, successful marketing of pharmaceuticals increases the returns from R&D, thus increasing incentives to explore consumer demand and to contribute to basic research on the role of drug therapy. Consumer benefits from this process may be very large.

摘要

主要针对医生的药品营销受到了批评,因为它可能会扭曲医生的处方行为,从而有可能提高成本和/或损害健康。本文提出的另一种观点是,成功的药品营销可以通过增加研发(R&D)投资的激励,并为研发提供指导,使其更符合消费者偏好,从而提高消费者福利。尽管药品营销存在诸多阻碍,如在美国禁止传播药品标签外信息、难以估计潜在药品需求以及需求评估与新药推出之间存在较长时间滞后,但仍有许多论据支持这一观点。例如,即使著名机构发布了新的循证实践指南,医生往往也迟迟不改变他们的处方习惯。药品推广可能特别有价值,因为信息起着关键作用,技术性很强,而且变化迅速。甚至消费者广告也可能潜在地改善健康,例如,通过提高患者对药物治疗的依从性。除了传播有关新疗法益处的信息外,药品推广的一个重要(也许是独特)作用是鼓励医生和支付方更加关注消费者对新医疗技术的需求(即支付意愿)。此外,成功的药品营销会增加研发回报,从而增加探索消费者需求和为药物治疗作用的基础研究做出贡献的激励。消费者从这一过程中获得的益处可能非常大。

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Off-label drug information: regulation, distribution, evaluation, and related controversies.药品未按说明书用药信息:监管、传播、评估及相关争议
P T. 2009 Aug;34(8):428-40.

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