Schott Daniel, Huffaker Tim, Bretscher Anthony
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
Curr Opin Microbiol. 2002 Dec;5(6):564-74. doi: 10.1016/s1369-5274(02)00369-7.
New evidence that cortical actin patches and the endocytic machinery share components supports the idea that actin patches are in fact transient membrane coats at the initial stage of endocytosis. Recent studies of actin cables have identified formins as the core of a novel actin-filament-assembling machine. Meanwhile, microtubule-binding proteins have been found in the kinetochore, and factors affecting microtubule dynamic instability have been identified.
皮质肌动蛋白斑块和内吞机制共享组件的新证据支持了这样一种观点，即肌动蛋白斑块实际上是内吞作用初始阶段的瞬时膜包被。最近对肌动蛋白丝束的研究已确定formin是一种新型肌动蛋白丝组装机器的核心。与此同时，在动粒中发现了微管结合蛋白，并鉴定出了影响微管动态不稳定性的因素。
