Hedley Anthony Johnson, Wong Chit-Ming, Thach Thuan Quoc, Ma Stefan, Lam Tai-Hing, Anderson Hugh Ross
Department of Community Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Lancet. 2002 Nov 23;360(9346):1646-52. doi: 10.1016/s0140-6736(02)11612-6.
In July, 1990, a restriction was introduced over one weekend that required all power plants and road vehicles in Hong Kong to use fuel oil with a sulphur content of not more than 0.5% by weight. This intervention led to an immediate fall in ambient sulphur dioxide (SO2). We assessed the effect of this intervention on mortality over the next 5 years.
Changes in trends in deaths were estimated by a Poisson regression model of deaths each month between 1985 and 1995. Changes in seasonal deaths immediately after the intervention were measured by the increase in deaths from warm to cool season. We also estimated the annual proportional change in number of deaths before and after the intervention. We used age-specific death rates to estimate person-years of life gained.
In the first 12 months after introduction of the restriction, a substantial reduction in seasonal deaths was noted, followed by a peak in the cool-season death rate between 13 and 24 months, returning to the expected pattern during years 3-5. Compared with predictions, the intervention led to a significant decline in the average annual trend in deaths from all causes (2.1%; p=0.001), respiratory (3.9%; p=0.0014) and cardiovascular (2.0%; p=0.0214) diseases, but not from other causes. The average gain in life expectancy per year of exposure to the lower pollutant concentration was 20 days (females) to 41 days (males).
Pollution resulting from sulphur-rich fuels has an effect on death rates, especially respiratory and cardiovascular deaths. The outcome of the Hong Kong intervention provides direct evidence that control of this pollution has immediate and long-term health benefits.
1990年7月的一个周末实施了一项限制措施,要求香港所有发电厂和道路车辆使用硫含量不超过0.5%(按重量计)的燃油。这一干预措施使环境中的二氧化硫(SO2)立即下降。我们评估了这一干预措施在接下来5年对死亡率的影响。
通过1985年至1995年每月死亡人数的泊松回归模型估计死亡趋势的变化。干预措施实施后立即通过从温暖季节到凉爽季节死亡人数的增加来衡量季节性死亡的变化。我们还估计了干预前后死亡人数的年度比例变化。我们使用特定年龄死亡率来估计获得的生命年数。
在实施限制措施后的前12个月,季节性死亡人数大幅减少,随后在13至24个月期间凉爽季节死亡率达到峰值,在第3至5年恢复到预期模式。与预测相比,该干预措施导致所有原因(2.1%;p = 0.001)、呼吸系统疾病(3.9%;p = 0.0014)和心血管疾病(2.0%;p = 0.0214)的平均年度死亡趋势显著下降,但其他原因导致的死亡趋势未下降。接触较低污染物浓度每年平均预期寿命增加20天(女性)至41天(男性)。
富含硫的燃料造成的污染对死亡率有影响,尤其是呼吸系统和心血管疾病导致的死亡。香港干预措施的结果提供了直接证据,表明控制这种污染对健康有即时和长期的益处。